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Cosméticos para grávidas – Desenvolvimento racional de um gel para pernas cansadas
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| 3.44 MB | Adobe PDF |
Authors
Abstract(s)
Esta dissertação contempla três capítulos inseridos no contexto da unidade curricular
“Estágio” do Mestrado Integrado em Ciências Farmacêuticas.
O primeiro capítulo é referente ao trabalho de investigação desenvolvido no Centro de
Investigação em Ciências da Saúde da Universidade da Beira Interior, intitulado
“Cosméticos para grávidas – Desenvolvimento racional de um gel para pernas cansadas”.
Durante a gravidez as mulheres experienciam inúmeras alterações fisiológicas e
hormonais. A pele sofre mudanças significativas, tais como hiperpigmentação, estrias, e
também alterações no cabelo e unhas. Este trabalho teve como objetivo avaliar o mercado
português de cosméticos para grávidas e, com base nesta informação, desenvolver um
produto cosmético para esta população. Foi conduzido um estudo de mercado em que se
analisaram os produtos cosméticos disponíveis no mercado nacional, e posteriormente,
foi desenvolvida uma formulação natural e minimalista de gel, especificamente para
pernas cansadas das grávidas. A estabilidade preliminar do gel foi avaliada através de
testes de centrifugação (3000 RPM, 30 min), testes de ciclos de temperatura (alternando
entre 4ºC e 40ºC diariamente, por 4 semanas), e por monitorização das características
organoléticas e pH ao longo do tempo. A caracterização reológica foi feita por
viscosímetro de cone-prato, com medições feitas em condições de temperatura
controlada (T=25ºC ± 2ºC), por 1 minuto (>5 rotações do cone). No final, obtivemos um
gel de aspeto homogéneo, translúcido/esbranquiçado e inodoro, que manteve a
estabilidade ao longo do tempo. A caracterização reológica classifica o gel como um fluido
não-Newtoniano, com comportamento pseudoplástico/ reofluidificante.
O segundo capítulo diz respeito ao meu estágio curricular em Farmácia Comunitária,
realizado na Farmácia Cordeiro, entre os dias 11 de setembro e 1 de dezembro de 2023,
sob orientação do Dr. Manuel Vieira. Neste capítulo são descritas várias experiências ao
longo do estágio, sendo abordados o modo de funcionamento de uma farmácia
comunitária e as responsabilidades dos farmacêuticos na sua atividade profissional.
O terceiro e último capítulo refere-se ao estágio curricular de Farmácia Hospitalar, no
Centro Hospitalar da Cova da Beira, no período de 4 de dezembro de 2023 a 26 de janeiro
de 2024, sob orientação da Dr.ª Maria Olímpia Fonseca. Ao longo do capítulo, são
descritas as áreas e as respetivas funções dos farmacêuticos hospitalares, assim como as
atividades realizadas durante o estágio.
This dissertation includes three chapters in the context of “Internship” curricular unit of the Integrated Master’s Degree in Pharmaceutical Sciences. The first chapter refers to the laboratory research work carried out at the Health Sciences Research Centre of the University of Beira Interior, entitled "Cosmetics for pregnant women - Rational development of a gel for tired legs". During pregnancy, women experience numerous physiological and hormonal changes. The skin undergoes significant changes, such as hyperpigmentation, stretch marks, and changes in the hair and nails. This study aimed to evaluate the Portuguese cosmetics market for pregnant women and based on this information, to develop a cosmetic product for this population. A market study analyzed the cosmetic products available on the Portuguese national market. A natural gel formulation specifically for tired legs in pregnant women was developed. Gel preliminary stability was evaluated through the centrifugation test (3000 RPM, 30min), and temperature cycle test (alternating 4ºC and 40ºC, daily, for 4 weeks), by monitoring the organoleptic characteristics and pH over time. Rheological characterization was conducted using a cone-plate viscometer, with measurements performed under controlled temperature conditions (T=25 °C ± 2 °C) for 1 minute (>5 cone revolutions). A homogeneous, translucent/white and odourless gel was obtained, which remained stable over time. Rheological characterization classifies the gel as a nonNewtonian fluid with pseudoplastic behavior. The second chapter concerns my Community Pharmacy internship, which took place at Farmácia Cordeiro between 11 September and 1 December 2023, under the supervision of Dr. Manuel Vieira. This chapter describes various experiences during the internship, covering the functioning of a community pharmacy and the responsibilities of pharmacists in their professional activity. The third and final chapter refers to the curricular internship in Hospital Pharmacy at the Centro Hospitalar da Cova da Beira, from 4 December 2023 to 26 January 2024, under the guidance of Dr Maria Olímpia Fonseca. Throughout the chapter, the areas and respective functions of hospital pharmacists are described, as well as the activities carried out during the internship.
This dissertation includes three chapters in the context of “Internship” curricular unit of the Integrated Master’s Degree in Pharmaceutical Sciences. The first chapter refers to the laboratory research work carried out at the Health Sciences Research Centre of the University of Beira Interior, entitled "Cosmetics for pregnant women - Rational development of a gel for tired legs". During pregnancy, women experience numerous physiological and hormonal changes. The skin undergoes significant changes, such as hyperpigmentation, stretch marks, and changes in the hair and nails. This study aimed to evaluate the Portuguese cosmetics market for pregnant women and based on this information, to develop a cosmetic product for this population. A market study analyzed the cosmetic products available on the Portuguese national market. A natural gel formulation specifically for tired legs in pregnant women was developed. Gel preliminary stability was evaluated through the centrifugation test (3000 RPM, 30min), and temperature cycle test (alternating 4ºC and 40ºC, daily, for 4 weeks), by monitoring the organoleptic characteristics and pH over time. Rheological characterization was conducted using a cone-plate viscometer, with measurements performed under controlled temperature conditions (T=25 °C ± 2 °C) for 1 minute (>5 cone revolutions). A homogeneous, translucent/white and odourless gel was obtained, which remained stable over time. Rheological characterization classifies the gel as a nonNewtonian fluid with pseudoplastic behavior. The second chapter concerns my Community Pharmacy internship, which took place at Farmácia Cordeiro between 11 September and 1 December 2023, under the supervision of Dr. Manuel Vieira. This chapter describes various experiences during the internship, covering the functioning of a community pharmacy and the responsibilities of pharmacists in their professional activity. The third and final chapter refers to the curricular internship in Hospital Pharmacy at the Centro Hospitalar da Cova da Beira, from 4 December 2023 to 26 January 2024, under the guidance of Dr Maria Olímpia Fonseca. Throughout the chapter, the areas and respective functions of hospital pharmacists are described, as well as the activities carried out during the internship.
Description
Keywords
Cosméticos Estudo de Mercado Farmácia
Hospitalar Farmácia Comunitária Gel Gravidez