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Abstract(s)
Este relatório para a obtenção do grau de mestre em Ciências Farmacêuticas está dividido em dois capítulos distintos, sendo que o capítulo I corresponde à componente de investigação e o capítulo II à componente de farmácia comunitária.
No capítulo I encontra-se o trabalho de investigação com o tema “Asma e doping”, que se baseia numa revisão bibliográfica sobre os agonistas beta 2 e corticosteróides que podiam ser usados no tratamento da asma em atletas de alta competição, os seus possíveis mecanismos de ação ergogénicos e os métodos para a deteção dos mesmos no controlo anti-doping.
A pesquisa de artigos científicos foi efetuada entre outubro de 2014 e setembro de 2015, nas plataformas de pesquisa Pubmed, Google scholar e nos sítios da Agência de Anti-doping Mundial,do Comité Olímpico Internacional e da Organização Mundial de Saúde.
Os resultados mostraram que o tratamento da asma atualmente permitido em atletas de alta competição é o adequado, permitindo o controlo adequado da patologia. No entanto, persistem dúvidas sobre se a terbutalina possui, ou não, características ergogénicas, que levaram as autoridades de antidopagem a torná-la uma substância proibida na prática desportiva. Concluiu-se também que as técnicas de deteção anti-doping usadas são também as mais adequadas, sendo muito precisas e sensíveis, com apenas a desvantagem de serem muito dispendiosas.
O capítulo II relata o estágio em farmácia comunitária efetuado na farmácia Misericórdia de Castro Daire, entre os meses de Janeiro e Junho de 2015. Neste estágio fui orientado pelo farmacêutico Francisco Barros e nas suas ausências, pela farmacêutica Ana Xavier. No final deste estágio, aprendi e experienciei o dia-a-dia de um farmacêutico numa farmácia comunitária.
This report consists in two different chapters: chapter I refers to the research and chapter II is related to the internship in community pharmacy. The research project, entittled “Asthma and doping” is based in a bibliographic review about the beta-2 agonists and corticosteroids that can be used in asthma treatment in elite athletes, its possible ergogenic mechanisms and the detection technics used for anti-doping control. The research of the scientific articles was made between October 2014 and September 2015, in the research platforms Pubmed and Google Scholar and the institutional sites of the World Anti-Doping Agency, the Internacional Olimpic Comitte and the World Health Organization. The results concluded that, nowadays, the treatment of asthma alowed in athletes is appropriate. However, some doubts related to terbutaline’s possible ergogenic mechanism, lead the anti-doping authorities to exclude this substance from the sports practice. We also concluded that the anti-doping detection technics currently in use are the most suitable because of is precision and sensitivity, with the only disadvantage of their high cost. The chapter II reports the internship in community pharmacy (Misericórdia Pharmacy) in Castro Daire, between February and June of 2015. In this internship I was supervised by Francisco Barros (pharmacist) and in his absences by Ana Xavier (pharmacist). During this internship, I learned and fully experienced the pharmacist activities in community pharmacy.
This report consists in two different chapters: chapter I refers to the research and chapter II is related to the internship in community pharmacy. The research project, entittled “Asthma and doping” is based in a bibliographic review about the beta-2 agonists and corticosteroids that can be used in asthma treatment in elite athletes, its possible ergogenic mechanisms and the detection technics used for anti-doping control. The research of the scientific articles was made between October 2014 and September 2015, in the research platforms Pubmed and Google Scholar and the institutional sites of the World Anti-Doping Agency, the Internacional Olimpic Comitte and the World Health Organization. The results concluded that, nowadays, the treatment of asthma alowed in athletes is appropriate. However, some doubts related to terbutaline’s possible ergogenic mechanism, lead the anti-doping authorities to exclude this substance from the sports practice. We also concluded that the anti-doping detection technics currently in use are the most suitable because of is precision and sensitivity, with the only disadvantage of their high cost. The chapter II reports the internship in community pharmacy (Misericórdia Pharmacy) in Castro Daire, between February and June of 2015. In this internship I was supervised by Francisco Barros (pharmacist) and in his absences by Ana Xavier (pharmacist). During this internship, I learned and fully experienced the pharmacist activities in community pharmacy.
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Keywords
Agonistas Beta-2 Asma Bie Doping Farmácia Comunitária