Browsing by Author "Del Giacco, Stefano"
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- ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergyPublication . Bousquet, Jean; Pfaar, Oliver; Agache, Ioana; Bedbrook, Anna; Akdis, Cezmi; Canonica, Giorgio Walter; Chivato, Tomas; Al-Ahmad, Mona; Rasib, A. H. Abdul; Ansotegui Zubeldia, Ignacio Javier; Bachert, Claus; Ispayeva, Zhanat; Bosnic-Anticevich, Sinthia; Recto, Marysia; Valiulis, Arunas; Durham, Stephen L; Gereda, Jose E; Schünemann, Holger; Levin, Michael; Zernotti, Mario; Fauquert, Jean-Luc; Sofiev, Mikhail; Kowalski, Marek; Chkhartishvili, Ekaterine; Bindslev-Jensen, Carsten; Wagenmann, Martin; Fontaine, Jean-François; Heffler, Enrico; Soto-Martinez, Manuel; Mahboub, Bassam; Jutel, Marek; Gerth Van Wijk, Roy; Lauerma, Antti; Ebisawa, Motohiro; Casale, Thomas; Bosse, Isabelle; Grisle, Ineta; Julge, Kaja; Barata, Luís Taborda; Meltzer, Eli O; Caraballo, Luis; Hoffmann-Sommergruber, Karin; Gawlik, Radoslaw; Devillier, Philippe; Chu, Derek K; Irani, Carla; Kraxner, Helga; Toppila-Salmi, Sanna; Montefort, Stephen; Nekam, Kristof; Kaidashev, Igor; Guzman, Maria Antonieta; El-Gamal, Yehia; Klimek, Ludger; Lau, Susanne; Valovirta, Erkka; Mullol, Joaquim; Palomares, Oscar; Ollert, Markus; O'Hehir, Robyn; Gelincik, Asli; Kvedarienė, Violeta; Wallace, Dana; Okubo, Kimihiro; Bergmann, Karl-Christian; Park, Hae-Sim; Papadopoulos, Nikolaos G.; Haahtela, Tari; Linnemann, Désirée Larenas; Wong, Gary Wk; Pham-Thi, Nhân; Martins, Pedro Carreiro; Regateiro, Frederico S.; Ivancevich, Juan Carlos; Malling, Hans-Jørgen; Zhang, Luo; Rottem, Menachem; Demoly, Pascal; Samoliński, Bolesław; Knol, Edward; Miculinic, Neven; Brough, Helen; Fiocchi, Alessandro; Sheikh, Aziz; Kritikos, Vicky; Almeida, Mário Morais; Cirule, Ieva; Gomez, R Maximiliano; Soto-Quiros, Manuel; Lodrup Carlsen, Karin C; Namazova-Baranova, Leyla; Ėmužytė, Regina; Bom, Ana Todo; Manning, Patrick; Pajno, Giovanni B; Gemicioglu, Bilun; Tsiligianni, Ioanna; Milenkovic, Branislava; Plavec, Davor; Halken, Susanne; Skypala, Isabel; O'Mahony, Liam; Fokkens, Wytske J; Lombardi, Carlo; Riggioni, Carmen; Shamji, Mohamed; Hossny, Elham; Vandenplas, Olivier; Mortz, Charlotte G; Rouadi, Philip; Tomazic, Peter Valentin; Passalacqua, Giovanni; Odemyr, Mikaëla; Marshall, Gailen D; Sanchez-Borges, Mario; Solé, Dirceu; Kalayci, Omer; Walusiak-Skorupa, Jolanta; Neffen, Hugo; Schmid-Grendelmeier, Peter; Roberts, Graham; Panzner, P.; Ohta, Ken; Scichilone, Nicola; Suppli-Ulrik, Charlotte; Kull, Inger; Yorgancıoglu, Arzu; Baharuddin, Abdullah; Sooronbaev, Talant; Serpa, Faradiba S; Patella, Vincenzo; Sova, Milan; Valero, Antonio; Laune, Daniel; Zidarn, Mihaela; Cardona, Victoria; Bonini, Matteo; Bjermer, Leif; Rodriguez-Gonzales, Monica; Torres, Maria J; Lourenço, Olga; Brussino, Luisa; Del Giacco, Stefano; Cepeda Sarabia, Alfonso M; Cecchi, Lorenzo; Sastre, Joaquin; Untersmayr, Eva; Melén, Erik; Cruz, Alvaro A; Niedoszytko, Marek; Dokic, Dejan; Sisul, Juan; Ventura, Maria Teresa; Moin, Mostafa; Gamkrelidze, Amiran; Palkonen, Susanna; Fonseca, Joao A; Schwarze, Jürgen; Wang, De Yun; Mösges, Ralph; Popov, Todor A; Gotua, Maia; Valentin Rostan, Marylin; Yusuf, Osman; Okamoto, Yoshitaka; Ryan, Dermot; Hrubiško, Martin; Urrutia-Pereira, Marilyn; Zuberbier, Torsten; Pawankar, Ruby; Khaitov, Musa; Vichyanond, Pakit; Calderon, Moises A; Rosário, Nelson; Kuna, Piotr; Waserman, Susan; Czarlewski, Wienczyslawa; Scadding, Glenis KAllergen immunotherapy (AIT), the gradually increasing repeated administration of high doses of allergens to allergic patients, offers the potential for immune tolerance against reactions to the natural exposures to specific allergens. AIT may lead to the long‐lasting remission of allergic symptoms and is the only disease‐modifying intervention in IgE‐mediated allergic respiratory diseases. [...]
- Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)Publication . Bousquet, Jean; Schünemann, Holger; Sousa-Pinto, Bernardo; Zuberbier, Torsten; Togias, Alkis; Samoliński, Bolesław; Bedbrook, Anna; Czarlewski, Wienczyslawa; Hofmann-Apitius, Martin; Litynska, Justyna; Vieira, Rafael José; Giuliano, Antonio F.M.; Gotua, Maia; Gradauskiene, Brigita; Guzman, Maria Antonieta; Hossny, Elham; Hrubiško, Martin; Iinuma, Tomohisa; Irani, Carla; Ispayeva, Zhanat; Ivancevich, Juan Carlos; Anto, Josep M.; Jartti, Tuomas; Jesenak, Milos; Julge, Kaja; Jutel, Marek; Kaidashev, Igor; Bennoor, Kazi Saifuddin; Khaltaev, Nicolai; Kirenga, Bruce; Kraxner, Helga; Kull, Inger; Fonseca, Joao A; Kulus, Marek; Kuna, Piotr; Kupczyk, Maciej; Kurchenko, Andriy; La Grutta, Stefania; Lane, Stephen; Miculinic, Neven; Lee, Sang Min; Le Thi Tuyet, Lan; Lkhagvaa, Battur; Brozek, Jan; Louis, Renaud; Mahboub, Bassam; Mäkelä, Mika J.; Makris, Michael; Maurer, Marcus; Melén, Eric; Milenkovic, Branislava; Mohammad, Yousser; Moniuszko, Marcin; Montefort, Stephen; Bognanni, Antonio; Moreira, Andre; Moreno, Pablo; Mullol, Joaquim; Nadif, Rachel; Nakonechna, Alla; Navarro-Locsin, Cecilia Gretchen; Neffen, Hugo; Nekam, Kristof; Niedoszytko, Marek; Nunes, Elizabete; Brussino, Luisa; Nyembue Tshipukane, Dieudonne; O’Hehir, Robyn; Ollert, Markus; Ohta, Ken; Okamoto, Yoshitaka; Okubo, Kimihiro; Olze, Heidi; Padukudru, Mahesh Anand; Palomares, Oscar; Pali-Schöll, Isabella; Canonica, Giorgio Walter; Panzner, Petr; Palosuo, Kati; Park, Hae-Sim; Passalacqua, Giovanni; Patella, Vincenzo; Pawankar, Ruby; Pétré, Benoît; Pitsios, Constantinos; Plavec, Davor; Popov, Todor A.; Cherrez Ojeda, Ivan; Puggioni, Francesca; Quirce, Santiago; Raciborski, Filip; Ramonaité, Agné; Recto, Marysia; Repka- Ramirez, María Susana; Roberts, Graham; Robles-Velasco, Karla; Roche, Nicolas; Rodriguez-Gonzalez, Monica; Cruz, Alvaro; Romualdez, Joel A.; Rottem, Menachem; Rouadi, Philip; Salapatas, Marianella; Sastre, Joaquin; Serpa, Faradiba; Sayah, Zineb; Scichilone, Nicola; Senna, Gianenrico; Sisul, Juan; Vecillas, Leticia De Las; Solé, Dirceu; Soto-Martinez, Manuel E.; Sova, Milan; Sozinova, Olga; Stevanovic, Katarina; Suppli Ulrik, Charlotte; Szylling, Anna; Tan, Frances M.; Tantilipikorn, Pongsakorn; Bom, Ana Todo; Dykewicz, Mark; Tomic Spiric, Vesna; Tsaryk, Vladyslav; Tsiligianni, Ioanna; Urrutia-Pereira, Marilyn; Valentin Rostan, Marylin; Sofiev, Mikhail; Valovirta, Erkka; Van Eerd, Michiel; Van Ganse, Eric; Vasankari, Tuula; Gemicioglu, Bilun; Vichyanond, Pakit; Viegi, Giovanni; Wallace, Dana; Wang, De Yun; Waserman, Susan; Wong, Gary; Worm, Margitta; Yusuf, Osman; Zaitoun, Fares; Zidarn, Mihaela; Giovannini, Mattia; Haahtela, Tari; Jacobs, Marc; Jacomelli, Cristina; Klimek, Ludger; Kvedarienė, Violeta; Linnemann, Désirée Larenas; Louis, Gilles; Lourenço, Olga; Leemann, Lucas; Almeida, Mario Morais; Neves, Ana Luisa; Nadeau, Kari; Nowak, Artur; Palamarchuk, Yuliia; Palkonen, Susanna; Papadopoulos, Nikolaos G.; Parmelli, Elena; Pereira, Ana Margarida; Pfaar, Oliver; Regateiro, Frederico S.; Savouré, Marine; Barata, Luís Taborda; Toppila-Salmi, Sanna Katriina; Torres, María Jose; Valiulis, Arunas; Ventura, Maria Teresa; Williams, Siân; Yepes-Nuñez, Juan J.; Yorgancıoglu, Arzu; Zhang, Luo; Zuberbier, Jaron; Abdul Latiff, Amir; Abdullah, Baharudin; Agache, Ioana; Al-Ahmad, Mona; Al-Nesf, Maryam A Y; Al Shaikh, A.; Amaral, Rita; Ansotegui Zubeldia, Ignacio Javier; Asllani, Julijana; Balotro-Torres, Maria Cristina; Bergmann, Karl-Christian; Bernstein, Jonathan; Bindslev-Jensen, Carsten; Blaiss, Michael S.; Bonaglia, Cristina; Bonini, Matteo; Bossé, Isabelle; Braido, Fulvio; Caballero-Fonseca, Fernan; Camargos, Paulo; Martins, Pedro Carreiro; Casale, Thomas; Castillo-Vizuete, José-Antonio; Cecchi, Lorenzo; Teixeira, Maria Do Céu; Chang, Yoon-Seok; Loureiro, Cláudia Chaves; Christoff, George; Ciprandi, Giorgio; Cirule, Ieva; Sousa, Jaime Correia De; Costa, Elísio; Cvetkovski, Biljana; De Vries, Govert; Del Giacco, Stefano; Devillier, Philippe; Dokic, Dejan; Douagui, Habib; Durham, Stephen; Enecilla, Maria Lourdes; Fiocchi, Alessandro; Fokkens, Wytske; Fontaine, Jean-François; Gawlik, Radoslaw; Gereda, Jose E.; Mata, Sara GilAbstract The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure that people's values and preferences guide clinical decisions. This paper reviews current knowledge to develop (1) digital care pathways for rhinitis and asthma multimorbidity and (2) digitally enabled, person-centered care.1 It combines all relevant research evidence, including the so-called real-world evidence, with the ultimate goal to develop digitally enabled, patient-centered care. The paper includes (1) Allergic Rhinitis and its Impact on Asthma (ARIA), a 2-decade journey, (2) Grading of Recommendations, Assessment, Development and Evaluation (GRADE), the evidence-based model of guidelines in airway diseases, (3) mHealth impact on airway diseases, (4) From guidelines to digital care pathways, (5) Embedding Planetary Health, (6) Novel classification of rhinitis and asthma, (7) Embedding real-life data with population-based studies, (8) The ARIA-EAACI (European Academy of Allergy and Clinical Immunology) strategy for the management of airway diseases using digital biomarkers, (9) Artificial intelligence, (10) The development of digitally enabled, ARIA person-centered care, and (11) The political agenda. The ultimate goal is to propose ARIA 2024 guidelines centered around the patient to make them more applicable and sustainable.
- Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: The ARIA‐MASK‐air® approachPublication . Bousquet, Jean; Anto, Josep M.; Sousa-Pinto, Bernardo; Czarlewski, Wienczyslawa; Bedbrook, Anna; Haahtela, Tari; Klimek, Ludger; Pfaar, Oliver; Kuna, Piotr; Kupczyk, Maciej; Regateiro, Frederico S.; Palamarchuk, Yuliia; Pépin, Jean‐Louis; Pétré, Benoit; Picard, Robert; Pitsios, Constantinos; Puggioni, Francesca; Quirce, Santiago; Raciborski, Filip; Reitsma, Sietze; Roche, Nicolas; Samolinski, Boleslaw; Rodriguez‐Gonzalez, Monica; Romantowski, Jan; Sousa, Ana Sá; Serpa, Faradiba S.; Savouré, Marine; Shamji, Mohamed H.; Sova, Milan; Sperl, Annette; Stellato, Cristiana; Todo‐Bom, Ana; Valiulis, Arunas; Tomazic, Peter Valentin; Vandenplas, Olivier; Van Eerd, Michiel; Vasankari, Tuula; Viart, Frédéric; Waserman, Susan; Fonseca, Joao A; Zuberbier, Torsten; Yorgancioglu, Arzu; Arnavielhe, Sylvie; Basagaña, Xavier; Bergmann, Karl C.; Bosnic‐Anticevich, Sinthia; Brussino, Luisa; Canonica, Giorgio Walter; Cardona, Victoria; Cecchi, Lorenzo; Loureiro, Cláudia Chaves; Costa, Elísio; Cruz, Alvaro A.; Gemicioglu, Bilun; Fokkens, Wytske; Ivancevich, Juan Carlos; Kraxner, Helga; Kvedariene, Violeta; Linnemann, Désirée E. Larenas; Laune, Daniel; Louis, Renaud; Makris, Michael; Maurer, Marcus; Melén, Erik; Micheli, Yann; Almeida, Mário Morais; Mullol, Joaquim; Niedoszytko, Marek; Okamoto, Yoshitaka; Papadopoulos, Nikolaos G.; Patella, Vincenzo; Pham‐Thi, Nhân; Rouadi, Philip W.; Sastre, Joaquin; Scichilone, Nicola; Sheikh, Aziz; Sofiev, Mikhail; Barata, Luís Taborda; Salmi, Sanna Toppila; Tsiligianni, Ioanna; Valovirta, Erkka; Ventura, Maria Teresa; Vieira, Rafael José; Zidarn, Mihaela; Amaral, Rita; Ansotegui, Ignacio J.; Bédard, Annabelle; Benveniste, Samuel; Bewick, Michael; Jensen, Carsten Bindslev; Blain, Hubert; Bonini, Matteo; Bourret, Rodolphe; Braido, Fulvio; Martins, Pedro Carreiro; Charpin, Denis; Cherrez‐Ojeda, Ivan; Chivato, Tomas; Chu, Derek K.; Cingi, Cemal; Del Giacco, Stefano; de Blay, Frédéric; Devillier, Philippe; De Vries, Govert; Doulaptsi, Maria; Doyen, Virginie; Dray, Gérard; Fontaine, Jean‐François; Gomez, R. Maximiliano; Hagemann, Jan; Heffler, Enrico; Hofmann, Maja; Jassem, Ewa; Jutel, Marek; Keil, Thomas; Kritikos, Vicky; Kull, Inger; Kulus, Marek; Lourenço, Olga; Mathieu‐Dupas, Eve; Menditto, Enrica; Mösges, Ralph; Murray, Ruth; Nadif, Rachel; Neffen, Hugo; Nicola, Stefania; O’Hehir, Robyn; Olze, HeidiMASK‐air®, a validated mHealth app (Medical Device regulationClass IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK‐air® is a Good Practice of DG Santé on digitally‐enabled, patient‐centred care. Itis also a candidate Good Practice ofOECD (Organisation for EconomicCo‐operation and Development). MASK‐air® data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK‐air® data show that most rhinitis patients (i) are not adherent and do notfollow guidelines, (ii) use as‐needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recom mended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom‐medication score (ARIA‐EAACI‐CSMS) has been validated for clinical practice and trials. The implications of the novel MASK‐air® results should lead to change management in rhinitis and asthma.
- Management of anaphylaxis due to COVID-19 vaccines in the elderlyPublication . Bousquet, Jean; Agache, Ioana; Blain, Hubert; Jutel, Marek; Ventura, Maria Teresa; Worm, Margitta; Del Giacco, Stefano; Benetos, Athanasios; Bilo, M Beatrice; Czarlewski, Wienczyslawa; Abdul Latiff, Amir; Cruz, Alvaro A; Dokic, Dejan; El-Gamal, Yehia; Atanaskovic-Markovic, Marina; Mullol, Joaquim; Khaitov, Musa; Louis, Renaud; Fernandez-Rivas, Montserrat; Fokkens, Wytske J; Fonseca, Joao A; Nekam, Kristof; O'Hehir, Robyn; Le Thi Tuyet, Lan; Miot, Stéphanie; Passalacqua, Giovanni; Lourenço, Olga; Namazova-Baranova, Leyla; Hofmann, Maja; Hrubisko, Martin; lenaIllario, Madda; Pfaar, Oliver; Niedoszytko, Marek; Popov, Todor A; Montella, Emma; Okamoto, Yoshitaka; Rondon, Carmen; Neffen, Hugo; Patella, Vincenzo; Knol, Edward; Kraxner, Helga; Kuna, Piotr; Salles, Nathalie; Odemyr, Mikaëla; Pham-Thi, Nhân; Le Moing, Vincent; Ollert, Markus; Recto, Marysia T; Scichilone, Nicola; Petrovic, Mirko; Rottem, Menachem; Mahler, Vera; Martin, Finbarr C; Matucci, Andrea; Hoffmann, Hans Jürgen; Skypala, Isabel; Plavec, Davor; Samolinski, Boleslaw; Almeida, Mário Morais; Regateiro, Frederico S; Mortz, Charlotte G; Sturm, Gunter; Rouadi, Philip W; Sediva, Anna; Torres, Maria; Santos, Alexandra F; Smolinska, Sylwia; Palomares, Oscar; Papadopoulos, Nikolaos G; Panzner, Petr; Valiulis, Arunas; Wallace, Dana; Shamji, Mohamed H; Suppli Ulrik, Charlotte; Zernotti, Mario; Sokolowska, Milena; Untersmayr, Eva; Roller-Winsberger, Regina E; Rolland, Yves; Romano, Antonino; Akdis, Cezmi A; Vitte, Joana; Al-Ahmad, Mona; Todo-Bom, Ana; Walusiak-Skorupa, Jolanta; Bennoor, Kazi Saifuddin; Urrutia-Pereira, Marilyn; Zidarn, Mihaela; Serpa, Faradiba Sarquis; Sastre, Joaquin; Schols, Jos M G A; Bosnic-Anticevich, Sinthia; Vultaggio, Alessandra; Zuberbier, Torsten; Sheikh, Aziz; Wang, De-Yun; Angier, Elizabeth; Carreiro-Martins, Pedro; Chivato, Tomas; Berghea, Elena Camelia; Sousa-Pinto, Bernardo; Sova, Milan; Stelmach, Rafael; Reynes, Jacques; Cherubini, Antonio; Klimek, Ludger; Brockow, Knut; Toppila-Salmi, Sanna; Annesi-Maesano, Isabella; Tsiligianni, Ioanna; Ebisawa, Motohiro; Bindslev-Jensen, Carsten; Carriazo, Ana; Gao, Yadong; Brussino, Luisa; Christoff, George; Waserman, Susan; Yorgancioglu, Arzu; Yusuf, Osman; Gelincik, Asli; Guérin, Olivier; Casale, Thomas; Eberlein, Bernadette; Irani, Carla; Chu, Derek K; Gavazzi, Gaëtan; Bachert, Claus; Barbaud, Annick; Bedbrook, Anna; Julge, Kaja; Gemicioglu, Bilun; Bonini, Sergio; Farrell, John; Haahtela, Tari; Kvedarienė, Violeta; Gawlik, Radolslaw; Ispayeva, Zhanat; Camargos, Paulo; Canonica, G Walter; Cardona, Victoria; Levin, Michael; Gotua, Maia; Kaidashev, Igor; Caubet, Jean-Christoph; Hoffmann-Sommergruber, Karin; Cecchi, Lorenzo; Milenkovic, Branislava; Ivancevich, Juan Carlos; Lauerma, AnttiOlder adults, especially men and/or those with diabetes, hypertension and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritised to receive COVID-19 vaccines due to high risk of death. In very rare instances,the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society)Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.