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  • Common Comorbidities in Avoidant/Restrictive Food Intake Disorder among Children and Adolescents: A systematic literature review
    Publication . Neves, Francisca Gomes Fernandes; Correia, Paula Cristina Moreira Antunes; Ferreira, Dário Jorge da Conceição
    Background and objectives: Avoidant/Restrictive Food Intake Disorder (ARFID) is a new feeding and eating disorder diagnosis recognized by the DSM-5 (2013) and ICD11 (2019). This systematic literature review aims to gather existing knowledge on the most common comorbidities amongst pediatric ARFID patients. Methods: This systematic literature review, adhering to PRISMA guidelines, focused on comorbidities in participants diagnosed with ARFID, specifically targeting those with a mean age below or equal to 18 years. A thorough search, covering the period from January 2013 to September 2023, was conducted across two databases, PubMed and BOn, resulting in the selection of 20 studies from an initial pool of 161 articles. The risk of bias was assessed using the ROBINS-I tool. Results: In regards to medical comorbidities, 8 studies had relevant information. From the observed comorbidities, 38% involved gastrointestinal symptoms in ARFID patients, and 25% indicated neurological conditions including migraines and sensory issues. Additionally, 10% of observations noted immune system complications such as food allergies and asthma. Psychiatric comorbidities were addressed in all but two included studies. From the instances observed, anxiety disorders were present in 45%, neurodevelopmental disorders like autistic spectrum disorder and attention deficit hyperactivity disorder in 33%, and mood disorders in 15%. The data also identified several other medical and psychiatric conditions. Conclusion: This review underscores the association between ARFID and diverse comorbidities, including gastrointestinal, neurological, and psychiatric conditions like anxiety and mood disorders. It highlights the disorder's complexity as well as its increased medical risks, advocating for early, multidisciplinary interventions and greater awareness among educators and health professionals. The need for comprehensive treatment involving various medical specialists is emphasized, along with the importance of family involvement and further research to enhance understanding and treatment of ARFID.
    2024-04-18Master thesis Open access Show more