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Abstract(s)
A balanite xerótica obliterante trata-se de uma doença de etiologia indeterminada, apesar das fortes evidências de etiologia auto-imune e associação com doenças de cariz auto-imune como hipertiroidismo, vitiligo, hipotiroidismo e DM I.
A BXO afeta principalmente indivíduos de raça caucasiana, não sendo muito comum a incidência da mesma em doentes com idade inferior a 2 anos.
A forte associação da patologia com o carcinoma peniano aliada a um constante subdiagnóstico pode contribuir para a prevalência aumentada de complicações como fimose, estenose do meato uretral e insuficiência renal obstrutiva, o que se traduz em mais gastos com a paliação e tratamento das consequências da BXO. A detecção precoce é um elemento chave na prevenção dessas mesmas complicações, sendo que a estratégia terapêutica de eleição – a circuncisão – é tecnicamente simples, acarreta poucos custos para o Sistema Nacional de Saúde e é extremamente eficaz enquanto medida terapêutica e preventiva.
Balanitis xerotica obliterans is a disease of undetermined etiology, despite strong evidence of autoimmune etiology and association with autoimmune diseases such as hyperthyroidism, vitiligo, hypothyroidism and DM I. BXO mainly affects individuals of Caucasian origin, and its incidence is not very common in patients younger than 2 years of age. The strong association of this disorder with penile cancer allied to a constant underdiagnosis can contribute to the increased prevalence of complications such as phimosis, meatal stenosis and renal failure, which translates into higher costs with palliation and treatment of the consequences of BXO. Early detection is a key element in the prevention of these same complications, and the therapeutic strategy of choice - circumcision - is technically simple, entails few costs to the National Health System and is extremely effective as a therapeutic and preventive measure.
Balanitis xerotica obliterans is a disease of undetermined etiology, despite strong evidence of autoimmune etiology and association with autoimmune diseases such as hyperthyroidism, vitiligo, hypothyroidism and DM I. BXO mainly affects individuals of Caucasian origin, and its incidence is not very common in patients younger than 2 years of age. The strong association of this disorder with penile cancer allied to a constant underdiagnosis can contribute to the increased prevalence of complications such as phimosis, meatal stenosis and renal failure, which translates into higher costs with palliation and treatment of the consequences of BXO. Early detection is a key element in the prevention of these same complications, and the therapeutic strategy of choice - circumcision - is technically simple, entails few costs to the National Health System and is extremely effective as a therapeutic and preventive measure.
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Keywords
Auto-Imune Balanite Xerótica Obliterante Carcinoma do Pénis Circuncisão Fimose Liquen Escleroso