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Abstract(s)
Introdução: A infertilidade foi reconhecida pela OMS como um problema de saúde pública, com implicações individuais, sociais e económicas nas sociedades contemporâneas. No entanto as Técnicas de Reprodução Medicamente Assistidas apresentam-se como solução para a infertilidade. De entre elas destaca-se Fertilização in-vitro e a Injeção intracitoplasmática cujos resultados importa estudar.
Objetivos: Avaliar os resultados obtidos com o tratamento de 2ª linha, Fertilização in vitro (FIV) ou Injeção intracitoplasmática (ICSI), nos casais que optaram por iniciar o tratamento para a infertilidade na Unidade de Medicina Reprodutiva do Centro Hospitalar da Cova da Beira e também, caracterizar as suas variáveis sociodemográficos e clinicas.
Método: Estudo epidemiológico de coorte retrospetivo, exploratório do tipo quantitativo, de nível descritivo, realizado em 78 casais submetidos a tratamento de segunda linha para infertilidade, FIV ou ICSI na Unidade de Medicina Reprodutiva do Centro Hospitalar Cova da Beira, no período entre Outubro de 2010 e Outubro de 2014.
Resultados: Dos 78 casais estudados verificou-se que 91,03% eram casados, sendo o grupo etário predominante o dos 30 - 34 anos, em que 46,15% eram do sexo feminino e 42,31% do masculino. O fator de infertilidade mais frequente no sexo feminino foi o tubar com 16,67% e no sexo masculino a teratozoospermia com 21,79%, sendo as causas de infertilidade em 34,62% atribuída ao sexo masculino. Em 29,49% dos casais a infertilidade durou entre os 13 e os 24 meses, em que a infertilidade primária estava presente em 70,51% dos casais.
A FIV foi utilizada em 65,38% dos casais, tendo-se obtido uma taxa de gravidez nos casais que realizaram a FIV de 26,79% e na ICSI de 32,14%. A taxa de recém-nascidos vivos (nos partos conhecidos) foi de 17,86% nos casais que realizaram FIV e de 25,00% nos que realizaram ICSI.
A causa mais frequente de infertilidade nos casais que realizaram a FIV foi feminina (31,37%) e nos que realizaram ICSI masculina (51,85%). Nas grávidas a causa final de infertilidade mais frequente nos casais que realizaram a ICSI foi masculina e mista (44,44%) e nos que realizaram FIV não existiu diferenciação entre masculina, feminina e mista (26,67%).
Discussão: As taxas de gravidez obtidas são sobreponíveis com os resultados a nível nacional e europeu, sendo as técnicas utilizadas por motivo de infertilidade consentâneas com as recomendações clínicas atuais.
Introduction: Infertility was recognized by the WHO as a public health issue with individual, social and economic implications in contemporary societies. Despite this, the Medically Assisted Reproduction Techniques have emerged as a solution for infertility. Among them, In-vitro fertilization and Intracytoplasmic Injection stand out, which merits the study of their results. Objectives: To evaluate the results obtained with the use of second-line treatment, In-vitro Fertilization (FIV) or Intracytoplasmic Injections (ICSI), in couples that opted to start infertility treatment at the Center for Human Reproduction of “Centro Hospitalar Cova da Beira”, as well as characterize their sociodemographic and clinical variables. Method: Retrospective and descriptive cohort study, carried out on 78 couples that underwent second-line treatment for infertility, FIV or ICSI at the Center for Human Reproduction of “Centro Hospitalar Cova da Beira”, in the period between October 2010 and October 2014. Results: Of the 78 couples, 91,03% were married, with the predominant age group being those with 30 to 34 years, in which 46,15% were female and 42,31% were male. The most common cause for infertility in women was tubal (with 16,67%) and in men teratozoospermia (with 21,79%). The cause of infertility in 34,62% of the couples was due to the male partner. In 29,49% of the couples, infertility lasted between 13 and 24 months, in which primary infertility was found to be present in 70,51% of these. FIV was used in 65,38% of the couples, which led to a 26,79% pregnancy rate in couples that underwent FIV, and 32,14% in those that underwent ICSI treatment. The rate of live births (in known child-births) was 17,86% in couples that underwent FIV and 25,00% in those that chose ICSI instead. The most frequent cause of infertility in couples that underwent FIV was female (31,37%). However, in couples that underwent ICSI treatment, the most frequent cause of infertility was male (51,85%). Discussion: The obtained pregnancy rates are comparable to the results of both national and European levels, with the techniques used consistent with current clinical recommendations.
Introduction: Infertility was recognized by the WHO as a public health issue with individual, social and economic implications in contemporary societies. Despite this, the Medically Assisted Reproduction Techniques have emerged as a solution for infertility. Among them, In-vitro fertilization and Intracytoplasmic Injection stand out, which merits the study of their results. Objectives: To evaluate the results obtained with the use of second-line treatment, In-vitro Fertilization (FIV) or Intracytoplasmic Injections (ICSI), in couples that opted to start infertility treatment at the Center for Human Reproduction of “Centro Hospitalar Cova da Beira”, as well as characterize their sociodemographic and clinical variables. Method: Retrospective and descriptive cohort study, carried out on 78 couples that underwent second-line treatment for infertility, FIV or ICSI at the Center for Human Reproduction of “Centro Hospitalar Cova da Beira”, in the period between October 2010 and October 2014. Results: Of the 78 couples, 91,03% were married, with the predominant age group being those with 30 to 34 years, in which 46,15% were female and 42,31% were male. The most common cause for infertility in women was tubal (with 16,67%) and in men teratozoospermia (with 21,79%). The cause of infertility in 34,62% of the couples was due to the male partner. In 29,49% of the couples, infertility lasted between 13 and 24 months, in which primary infertility was found to be present in 70,51% of these. FIV was used in 65,38% of the couples, which led to a 26,79% pregnancy rate in couples that underwent FIV, and 32,14% in those that underwent ICSI treatment. The rate of live births (in known child-births) was 17,86% in couples that underwent FIV and 25,00% in those that chose ICSI instead. The most frequent cause of infertility in couples that underwent FIV was female (31,37%). However, in couples that underwent ICSI treatment, the most frequent cause of infertility was male (51,85%). Discussion: The obtained pregnancy rates are comparable to the results of both national and European levels, with the techniques used consistent with current clinical recommendations.
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Keywords
Fertilização In Vitro Infertilidade Injeção Intracitoplasmática Reprodução Medicamente Assistida