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Abstract(s)
O presente relatório de estágio encontra-se inserido na unidade curricular Estágio Curricular do Mestrado Integrado de Ciências Farmacêuticas. Deste trabalho constam três partes: a primeira referente ao trabalho de pesquisa bibliográfica, uma revisão da literatura no âmbito da toxicidade da Mitragyna speciosa, o seu consumo como droga de abuso bem como o seu doseamento; a segunda aborda o estágio curricular realizado em farmácia comunitária e a terceira aborda o estágio curricular realizado em farmácia hospitalar.
O primeiro capítulo intitula-se “Mitragyna speciosa: aspetos analíticos e toxicológicos” e explora a planta Mitragyna speciosa. O uso de substâncias para, de certa forma, beneficiar dos seus efeitos é um fenómeno bem conhecido, e muitas dessas substâncias são geralmente associadas a tradições ancestrais e remédios caseiros. É o caso da Mitragyna speciosa (kratom), uma árvore tropical que foi inicialmente usada principalmente no Sudeste Asiático para melhorar o desempenho no trabalho e suportar condições térmicas severas. Devido ao facto de que se encontra disponível na internet para compra, o seu uso está agora amplamente difundido, tornando-se uma questão importante sobre a qual não existe ainda informação suficiente. A pesquisa bibliográfica realizada pretende então dar uma visão sobre o kratom. O objetivo principal é compreender a sua origem, formas e razões para consumo, metodologias analíticas, mecanismo de ação e, portanto, os seus efeitos clínicos, assim como os seus potenciais riscos com base numa série de estudos realizados até à data.
O segundo capítulo é referente ao estágio curricular que desenvolvi na farmácia do Sameiro, em Penafiel. Neste capítulo são descritas as competências técnicas desenvolvidas no âmbito da realidade farmacêutica no contexto de farmácia comunitária.
O terceiro capítulo é referente ao estágio curricular que desenvolvi na Unidade local de Saúde da Guarda (ULSG), onde são descritas todas as atividades desenvolvidas e competências adquiridas, desta vez num contexto de farmácia hospitalar.
The present report is part of a curricular unit named Internship of Integrated Master in Pharmaceutical Sciences. This work is divided into three parts: the first one concerns a bibliographical review on the toxicity of Mitragyna speciosa, its consumption as drug of abuse and its measurement in samples of different origin. The second part refers to the curricular internship that took place in a community pharmacy, while the third part refers to the curricular internship that took place in a hospital pharmacy. The first chapter is entitled “Mitragyna speciosa: analytical and toxicological aspects” and explores the plant Mitragyna speciosa. The use of substances to, in some way, benefit from their effects is a well-known phenomenon, and many of these substances are usually associated to ancestral traditions and home remedies. This is the case of Mitragyna speciosa (kratom), a tropical tree that was initially mostly used in Southeast Asia to improve work performance and to withstand great heat situations. Due to the fact that it is available on the internet for purchase, its use is now widely spread, becoming an important issue, due to the lack of adequate information. This chapter intends to give a close insight about kratom. The main goal is to understand its origin, consumption, analytical methodologies for analysis, mechanism of action and clinical effects and potential risks, based on a series of studies performed so far. The second chapter refers to the curricular internship I developed at the Farmácia do Sameiro in Penafiel. This chapter describes the technical competences developed within the scope of the pharmaceutical reality in the context of community pharmacy. The third chapter refers to the curricular internship that I developed at the Unidade local de Saúde da Guarda (ULSG), where all the activities developed and skills acquired are described, this time in a hospital pharmacy context.
The present report is part of a curricular unit named Internship of Integrated Master in Pharmaceutical Sciences. This work is divided into three parts: the first one concerns a bibliographical review on the toxicity of Mitragyna speciosa, its consumption as drug of abuse and its measurement in samples of different origin. The second part refers to the curricular internship that took place in a community pharmacy, while the third part refers to the curricular internship that took place in a hospital pharmacy. The first chapter is entitled “Mitragyna speciosa: analytical and toxicological aspects” and explores the plant Mitragyna speciosa. The use of substances to, in some way, benefit from their effects is a well-known phenomenon, and many of these substances are usually associated to ancestral traditions and home remedies. This is the case of Mitragyna speciosa (kratom), a tropical tree that was initially mostly used in Southeast Asia to improve work performance and to withstand great heat situations. Due to the fact that it is available on the internet for purchase, its use is now widely spread, becoming an important issue, due to the lack of adequate information. This chapter intends to give a close insight about kratom. The main goal is to understand its origin, consumption, analytical methodologies for analysis, mechanism of action and clinical effects and potential risks, based on a series of studies performed so far. The second chapter refers to the curricular internship I developed at the Farmácia do Sameiro in Penafiel. This chapter describes the technical competences developed within the scope of the pharmaceutical reality in the context of community pharmacy. The third chapter refers to the curricular internship that I developed at the Unidade local de Saúde da Guarda (ULSG), where all the activities developed and skills acquired are described, this time in a hospital pharmacy context.
Description
Keywords
7-Hidroximitraginina Farmácia Comunitária Farmácia Hospitalar Kratom Mitraginina Mitragyna Speciosa Opióide Toxicodependência