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Advisor(s)
Abstract(s)
Introdução: A diabetes e o hipotiroidismo são duas das doenças endócrinas mais comuns,
ambas com repercussão sistémica no organismo, quer pelo seu efeito a curto prazo quer
pelas suas consequências a longo prazo. Estas são patologias que, isoladamente, estão
associadas a complicações semelhantes, nomeadamente na função cardiovascular e
metabólica, o que pode sugerir uma sinergia entre ambas. A diabetes é a doença endócrina
crónica mais comum caracterizada por um estado de hiperglicemia devido a
anormalidades na secreção de insulina e/ou na sua ação, estando associada a lesões de
órgão-alvo. O hipotiroidismo resulta de uma queda na produção de hormonas tiroideias
com níveis aumentados de TSH (thyroid-stimulating hormone). Verifica-se ainda que o
hipotiroidismo é, por si só, um fator de risco para o desenvolvimento de diabetes, já que
dados demonstram uma maior prevalência de doentes diabéticos em amostras de doentes
com hipotiroidismo em comparação com a população geral. Evidências sugerem ainda
que a diabetes gestacional associada ao hipotiroidismo constitui um fator de risco para
complicações da gravidez, tais como rotura prematura de membranas e anomalias do
crescimento intrauterino, assim como complicações futuras no feto.
Métodos: Para a realização deste trabalho, efetuou-se a pesquisa na internet de artigos
científicos relacionados com o tema utilizando como motores de busca o PubMed e Google
Scholar.
Objetivo: Averiguar a possível relação entre todas as formas de diabetes, nomeadamente
diabetes tipo 1, diabetes tipo 2 e diabetes gestacional e o hipotiroidismo
Conclusão: Há uma associação entre o hipotiroidismo e a diabetes. Assim, torna-se
necessário realizar mais pesquisas para investigar as causas subjacentes desta associação e
desenvolver abordagens diagnósticas e terapêuticas direcionadas. O rastreio analítico
apertado e periódico destes doentes beneficia a prevenção do surgimento das doenças e
complicações inerentes às mesmas, pelo que deve ser feita uma monitorização da função
tiroideia em doentes diabéticos.
Introduction: Diabetes and hypothyroidism are two of the most common endocrine diseases, both with systemic repercussions in the body, either due to their short-term effect or their long-term consequences. These are pathologies that are assiduously associated with similar complications, namely in cardiovascular and metabolic function, which may suggest a synergy between both. Diabetes is a chronic endocrine disease characterized by a state of hyperglycemia due to abnormalities in insulin secretion and/or its action and is associated with target organ damage. Hypothyroidism results from a drop in the production of thyroid hormones with increased levels of TSH (Thyroid Stimulating Hormone). It is also verified that hypothyroidism is a risk factor for the development of diabetes, since the data demonstrate a higher prevalence of diabetic patients in patients with hypothyroidism compared to the general population. Evidence also suggests that gestational diabetes associated with hypothyroidism is a risk factor for pregnancy complications, such as premature rupture of membranes and intrauterine growth abnormalities, as well as future complications in the fetus. Methods: To carry out this work, a search was made on the internet for scientific articles related to the subject using PubMed and Google Scholar as search engines. Objective: To verify the possible relationship between all forms of diabetes, namely type 1 diabetes, type 2 diabetes and gestational diabetes and hypothyroidism Conclusion: There is an association between hypothyroidism and diabetes. Thus, further investigation of the underlying causes of this association is needed to develop targeted diagnostic and therapeutic approaches. The tight and periodic analytical screening of these patients benefits the prevention of the onset of diseases and complications inherited to them, which is why thyroid function monitoring should be performed in diabetic patients.
Introduction: Diabetes and hypothyroidism are two of the most common endocrine diseases, both with systemic repercussions in the body, either due to their short-term effect or their long-term consequences. These are pathologies that are assiduously associated with similar complications, namely in cardiovascular and metabolic function, which may suggest a synergy between both. Diabetes is a chronic endocrine disease characterized by a state of hyperglycemia due to abnormalities in insulin secretion and/or its action and is associated with target organ damage. Hypothyroidism results from a drop in the production of thyroid hormones with increased levels of TSH (Thyroid Stimulating Hormone). It is also verified that hypothyroidism is a risk factor for the development of diabetes, since the data demonstrate a higher prevalence of diabetic patients in patients with hypothyroidism compared to the general population. Evidence also suggests that gestational diabetes associated with hypothyroidism is a risk factor for pregnancy complications, such as premature rupture of membranes and intrauterine growth abnormalities, as well as future complications in the fetus. Methods: To carry out this work, a search was made on the internet for scientific articles related to the subject using PubMed and Google Scholar as search engines. Objective: To verify the possible relationship between all forms of diabetes, namely type 1 diabetes, type 2 diabetes and gestational diabetes and hypothyroidism Conclusion: There is an association between hypothyroidism and diabetes. Thus, further investigation of the underlying causes of this association is needed to develop targeted diagnostic and therapeutic approaches. The tight and periodic analytical screening of these patients benefits the prevention of the onset of diseases and complications inherited to them, which is why thyroid function monitoring should be performed in diabetic patients.
Description
Keywords
Diabetes Diabetes Gestacional Hipotiroidismo Hipotiroidismo Subclínico Outcomes