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Advisor(s)
Abstract(s)
Este relatório de estágio encontra-se dividido em dois capítulos, o primeiro relativo à
vertente de investigação e o segundo relativo ao estágio em farmácia comunitária.
No primeiro capítulo é abordado o perfil de utilização, efeitos secundários e potenciais
interações medicamentosas de fármacos antiulcerosos pela população portuguesa. Para isso,
realizou-se um estudo observacional em Farmácias Comunitárias de vários distritos de
Portugal, e a amostra foi composta por 200 utentes que utilizavam ou utilizaram
antiulcerosos. A informação foi obtida através de inquéritos individuais e anónimos. Para o
tratamento de dados recorreu-se ao programa SPSS, versão 23 e do Excel. Dos 200 inquiridos,
com idades compreendidas entre os 19 e os 90 anos, a média de idades foi 57 anos e 115 eram
mulheres (57,5%). Os fármacos mais utilizados concomitantemente com os antiulcerosos
foram os anti-hipertensores (18,84%), seguido dos anti-inflamatórios não esteróides (12,56%),
dos antidislipidémicos (11,31%) e do ácido acetilsalicílico (6,79). Adicionalmente, verificou-se
o uso de muitos suplementos como é o caso de associações de vitaminas (4,27%), ferro
(1,01%), magnésio e cálcio (0,50% e 1,01%, respetivamente).
A classe de antiulcerosos mais utilizados foram os inibidores da bomba de protões, sendo o
omeprazol o mais usado dentro desta classe. Verificou-se, ainda, que 56,5% (87 pessoas)
tomavam anti-ulcerosos diariamente, e, destes, 49% os tomavam há menos de 1 ano, e 30,5%
há mais de 5 anos. Além disso, observou-se que em 40% dos inquiridos o medicamento foi
prescrito pelo médico de família e que em grande parte da amostra foi por automedicação.
De uma forma geral, não foram detetados efeitos adversos relevantes, e os que os
destacavam eram principalmente os utentes que os utilizavam de toma incorreta.
Assim, deste projeto de investigação, conclui-se que as mulheres utilizam mais fármacos
antiulcerosos do que os homens e que os inibidores da bomba de protões são os fármacos mais
prescritos. É importante realçar ainda que os antiulcerosos, após um longo período de tempo
podem causar efeitos indesejáveis e, por isso, é uma mais valia o acompanhamento e
monitorização da medicação, não só para o sucesso terapêutico, como para evitar a utilização
excessiva dos mesmos.
No segundo capítulo, pretendeu-se abordar as áreas de funcionamento de uma farmácia
comunitária, bem como as responsabilidades de um farmacêutico nesse contexto. O estágio
realizou-se na Farmácia Central entre 21 de janeiro e 12 de junho de 2015, perfazendo um
período total de 800 horas. Esta experiência permitiu ter consciência do profundo dever
social e conhecimento multidisciplinar de um farmacêutico, bem como o papel ativo e fundamental deste na vida de cada doente. A ciência está em constante mudança, sendo
fulcral a constante atualização profissional nas diversas áreas científicas.
This document is divided in two chapters, the first is related to a research study and the second focused on the internship in community pharmacy. In the first chapter, the main focus consists the usage profile, secondary effects, potential drug interactions of antiulcer drugs by a Portuguese population. For this, an observational study was held in Community Pharmacies in several districts of Portugal, through a 200 user sample, who use or have used anti-ulcer medications. The information was obtained through individual and anonymous inquiries. The data was compiled using SPSS program, version 23 and Excel. Of the 200 respondents, aged between 19 and 90 years old, the average age was 57 years and 115 were women (57.5%). The top concurrently used drugs were the antihypertensives (18.84%), then the non-steroidal anti-inflammatory drugs (12.56%),-anti-dyslipidemics (11.31%) and acetylsalicylic acid (6.79). It was also found a relevant use of many supplements such as vitamin associations (4.27%), iron (1.01%), magnesium and calcium (0.50% and 1.01%, respectively). The most widely used anti-ulcer drugs were the proton pump inhibitors, being omeprazol the most used within this class. 56.5% (87 patients) took it regularly, and within these 49% for less than 1 year, and 30.5% for more than 5 years. The study also showed that in 40% of the respondents, these drugs were acquired after family doctor prescriptions. However in the great majority of the population these drugs were used after self-medication. In general, major adverse effects weren’t detected, and those highlighted were mainly associated to incorrect use. Through this research project, it was concluded that women use more anti-ulcer drugs than men, being the proton pump inhibitors the top prescribed. It is important to highlight that anti-ulcer medication after a long period of time can cause unwanted effects, and is therefore important to keep track and monitor the medication, not only to improve the therapeutic success, but to avoid the excessive use. The purpose of the second chapter was to address the operational areas of a community pharmacy as well as the responsibilities of the pharmacist. The training course was held in “Farmária Central”, between January 21 and June 12, 2015, with a total duration of 800 hours. This training promoted the awareness of the profound social duty and multidisciplinary knowledge of a pharmacist, as well as the active and important role in each patient’s lives. Science is constantly changing, increasing the responsibility of a constant professional update in several scientific areas.
This document is divided in two chapters, the first is related to a research study and the second focused on the internship in community pharmacy. In the first chapter, the main focus consists the usage profile, secondary effects, potential drug interactions of antiulcer drugs by a Portuguese population. For this, an observational study was held in Community Pharmacies in several districts of Portugal, through a 200 user sample, who use or have used anti-ulcer medications. The information was obtained through individual and anonymous inquiries. The data was compiled using SPSS program, version 23 and Excel. Of the 200 respondents, aged between 19 and 90 years old, the average age was 57 years and 115 were women (57.5%). The top concurrently used drugs were the antihypertensives (18.84%), then the non-steroidal anti-inflammatory drugs (12.56%),-anti-dyslipidemics (11.31%) and acetylsalicylic acid (6.79). It was also found a relevant use of many supplements such as vitamin associations (4.27%), iron (1.01%), magnesium and calcium (0.50% and 1.01%, respectively). The most widely used anti-ulcer drugs were the proton pump inhibitors, being omeprazol the most used within this class. 56.5% (87 patients) took it regularly, and within these 49% for less than 1 year, and 30.5% for more than 5 years. The study also showed that in 40% of the respondents, these drugs were acquired after family doctor prescriptions. However in the great majority of the population these drugs were used after self-medication. In general, major adverse effects weren’t detected, and those highlighted were mainly associated to incorrect use. Through this research project, it was concluded that women use more anti-ulcer drugs than men, being the proton pump inhibitors the top prescribed. It is important to highlight that anti-ulcer medication after a long period of time can cause unwanted effects, and is therefore important to keep track and monitor the medication, not only to improve the therapeutic success, but to avoid the excessive use. The purpose of the second chapter was to address the operational areas of a community pharmacy as well as the responsibilities of the pharmacist. The training course was held in “Farmária Central”, between January 21 and June 12, 2015, with a total duration of 800 hours. This training promoted the awareness of the profound social duty and multidisciplinary knowledge of a pharmacist, as well as the active and important role in each patient’s lives. Science is constantly changing, increasing the responsibility of a constant professional update in several scientific areas.
Description
Keywords
Ciências Farmacêuticas Farmácia Comunitária Fármacos Antiulcerosos Úlceras