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Abstract(s)
O presente relatório foi realizado no âmbito da Unidade Curricular de Estágio e
destina-se à obtenção do grau de Mestre em Ciências Farmacêuticas. É constituído por
dois capítulos: o Capítulo 1 corresponde à componente de Investigação, e o Capítulo 2
diz respeito ao relatório de estágio em Farmácia Comunitária.
O Capítulo 1 aborda o potencial das plantas medicinais como uma alternativa
terapêutica para o tratamento da insónia. É amplamente reconhecido que uma boa
qualidade de sono desempenha um papel fundamental na saúde e no bem-estar geral,
no entanto, a insónia é um distúrbio do sono comum. A prevalência da insónia é de
aproximadamente 30% da população, e 10% tem sintomas que satisfazem os critérios
do Manual Diagnóstico e Estatístico de Transtornos Mentais 5.ª edição (Diagnostic and
Statistical Manual of Mental Disorders Fifth Edition, DSM-5). A qualidade de vida é
profundamente afetada pela insónia devido às sequelas associadas, incluindo prejuízos
na cognição, humor e funcionalidade. Para além da relação bidirecional que tem com
outros distúrbios, como depressão e ansiedade. Com o aumento da preocupação com os
efeitos adversos dos medicamentos convencionais, há um interesse crescente em
explorar substâncias derivadas de fontes naturais, como plantas medicinais, que
possam promover um sono saudável de maneira segura e eficaz. Através da base de
dados Pubmed foi possível identificar plantas que podem ser utilizadas como auxiliares
no sono. A pesquisa abrange a identificação de plantas medicinais conhecidas e
estudadas pelas suas propriedades sedativas e relaxantes, os seus constituintes ativos
com efeito anti-insónia, possíveis mecanismos subjacentes, bem como efeitos adversos
relatos e cuidados a ter. No geral, as plantas apresentam benefícios na melhoria da
quantidade e qualidade do sono e podem ser uma terapia alternativa promissora na
insónia. Desta forma, o objetivo na componente de investigação foi identificar,
sintetizar e discutir possíveis alternativas fitoterápicas que possam ser utilizadas para o
tratamento da insónia.
O Capítulo 2 diz respeito ao estágio curricular em Farmácia Comunitária, realizado na
Farmácia Barreiro, situada em Chaves, entre 12 de setembro de 2023 a 31 de janeiro de
2024, sob a orientação da Dr.ª Teresa Barreiro. Este capítulo explora o funcionamento
da farmácia e os conhecimentos teóricos, assim como as experiências práticas que pude
vivenciar ao longo do estágio.
The present report was prepared within the scope of the Internship Curricular Unit and is intended to obtain the degree of Master in Pharmaceutical Sciences. It consists of two chapters: Chapter 1 corresponds to the research component, and Chapter 2 pertains to the internship report in Community Pharmacy. Chapter 1 addresses the potential of medicinal plants as a therapeutic alternative for the treatment of insomnia. It is widely recognized that good sleep quality plays a fundamental role in health and overall well-being, however, insomnia is a common sleep disorder. The prevalence of insomnia is a approximately 30% of the population, and 10% have symptoms that meet the criteria of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Quality of life is profoundly affected by insomnia due to associated sequelae, including impairments in cognition, mood, and functionality. Additionally, there is a bidirectional relationship with other disorders such as depression and anxiety. With the growing concern about the adverse effects of conventional medications, there is increasing interest in exploring substances derived from natural sources, such as medicinal plants, that can promove healthy sleep safely and effectively. Through the PubMed datebase, it was possible to identify plants that can be used as sleep aids. The research covers the identification of medicinal plants known and studied for their sedative and relaxing properties, their active constituents with anti-insomnia effects, possible underlying mechanisms, as well as reported adverse effects and precautions. Overall, plants presente benefits in improving the quantity and quality of sleep and may be a promising alternative therapy for insomnia. Therefore, the aim of the research componente was to identify, synthesize, and discuss possible herbal alternatives that can be used for the treatment of insomnia. Chapter 2 pertains to the curricular internship in Community Pharmacy, carried out at Farmácia Barreiro, located in Chaves, from September 12, 2023, to January 31, 2024, under the supervision of Dr. Teresa Barreiro. This chapter explores the operation of the pharmacy and the theoretical knowledge, as well as the practical experiences I was able to gain throughout the internship.
The present report was prepared within the scope of the Internship Curricular Unit and is intended to obtain the degree of Master in Pharmaceutical Sciences. It consists of two chapters: Chapter 1 corresponds to the research component, and Chapter 2 pertains to the internship report in Community Pharmacy. Chapter 1 addresses the potential of medicinal plants as a therapeutic alternative for the treatment of insomnia. It is widely recognized that good sleep quality plays a fundamental role in health and overall well-being, however, insomnia is a common sleep disorder. The prevalence of insomnia is a approximately 30% of the population, and 10% have symptoms that meet the criteria of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Quality of life is profoundly affected by insomnia due to associated sequelae, including impairments in cognition, mood, and functionality. Additionally, there is a bidirectional relationship with other disorders such as depression and anxiety. With the growing concern about the adverse effects of conventional medications, there is increasing interest in exploring substances derived from natural sources, such as medicinal plants, that can promove healthy sleep safely and effectively. Through the PubMed datebase, it was possible to identify plants that can be used as sleep aids. The research covers the identification of medicinal plants known and studied for their sedative and relaxing properties, their active constituents with anti-insomnia effects, possible underlying mechanisms, as well as reported adverse effects and precautions. Overall, plants presente benefits in improving the quantity and quality of sleep and may be a promising alternative therapy for insomnia. Therefore, the aim of the research componente was to identify, synthesize, and discuss possible herbal alternatives that can be used for the treatment of insomnia. Chapter 2 pertains to the curricular internship in Community Pharmacy, carried out at Farmácia Barreiro, located in Chaves, from September 12, 2023, to January 31, 2024, under the supervision of Dr. Teresa Barreiro. This chapter explores the operation of the pharmacy and the theoretical knowledge, as well as the practical experiences I was able to gain throughout the internship.
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Keywords
Farmácia Comunitária Insónia Plantas Medicinais Sono