| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 7.26 MB | Adobe PDF |
Authors
Abstract(s)
O trabalho que se segue representa a etapa final do Mestrado Integrado em Ciências
Farmacêuticas, para a obtenção do grau de Mestre e encontra-se dividido em três capítulos. O
primeiro capítulo intitula-se “Enquadramento Regulamentar do uso dos subprodutos da
Cannabis sativa L. em Produtos Cosméticos” e diz respeito ao trabalho de investigação
realizado sobre a utilização da Cannabis sativa L. e seus subprodutos no setor cosmético e o
respetivo enquadramento regulamentar, sob orientação da Professora Doutora Ana Palmeira de
Oliveira e co-orientação da Professora Doutora Rita Palmeira de Oliveira. Parte do trabalho
apresentado neste primeiro capítulo decorreu no contexto do projeto “PAM4WELLNESS -
Código da Operação: POCI-04—SIAC-2021-181319, Transferência do Conhecimento cientifico e
tecnológico, COMPETE, Portugal2020”. O segundo capítulo descreve a experiência
profissionalizante obtida durante o meu estágio na Unidade Local de Saúde da Guarda, em
farmácia hospitalar, sob supervisão da Dra. Carmo Teixeira. Por sua vez, o terceiro capítulo
relata a minha experiência profissionalizante no âmbito de farmácia comunitária, na Farmácia
Ideal, sob a supervisão da Dra. Raquel Ramalheira.
O primeiro capítulo prende-se com a análise e caracterização dos subprodutos da Cannabis
sativa L. sem alucinogénios com interesse na área Cosmética, fazendo um ponto de situação do
seu enquadramento regulamentar, em especial no mercado europeu e dos EUA.
A utilização da Cannabis sativa L. na sociedade remonta há vários séculos atrás, tendo a sua
utilização para fins recreativos, medicinais e mais recentemente em produtos cosméticos
passado por um contexto evolutivo, a nível mundial, de períodos de maior e menor tolerância ao
seu uso.
Para este trabalho, importou, inicialmente, caracterizar a planta e contextualizar
evolutivamente o seu consumo e utilização. Compreendeu-se que o interesse pela planta e pelos
seus subprodutos está em crescimento exponencial, o que levou a um estudo mais aprofundado
dos ingredientes à base da planta e o seu uso potencial em cosmética. No entanto, este uso
levanta questões regulamentares e de sustentação científica que garantam a sua utilização
segura em produtos cosméticos.
A nível regulamentar e legislativo existe atualmente uma grande discrepância entre os
diferentes mercados, e também dentro do próprio mercado europeu e dos Estados Unidos da
América. No entanto, espera-se que no ano de 2024 haja um conjunto de medidas conjuntas com o objetivo de harmonizar a legislação a nível mundial e facilitar, com base em sustentação
científica credível, a resposta às necessidades dos consumidores.
Com o estudo mais aprofundado sobre estes ingredientes cosméticos à base da Cannabis sativa
L. e dos seus subprodutos tem sido possível refletir no impacto positivo que os mesmos têm
demonstrado para inúmeras patologias da pele.
O segundo capítulo refere-se às atividades desenvolvidas ao longo do meu estágio em Farmácia
Hospitalar, no Hospital Nossa Senhora da Assunção e no Hospital Sousa Martins, que decorreu
de 27 de março a 19 de maio de 2023. Neste capítulo são descritas todas as áreas em que o
farmacêutico hospitalar atua e o contexto nos hospitais onde me encontrei inserida. Importa
mencionar que descrevo detalhadamente todos os processos inerentes ao bom funcionamento
dos serviços farmacêuticos hospitalares e faço uma reflexão da minha aprendizagem durante o
estágio e a importância que o mesmo teve na minha formação.
No terceiro capítulo são descritas as atividades que realizei na Farmácia Ideal de 22 de maio a
14 de agosto de 2023. Neste, são relatadas todas as atividades e processos necessários ao
desenvolvimento eficiente das tarefas e responsabilidades atribuídas ao farmacêutico. Durante
este estágio, consegui consolidar muitos dos conhecimentos teóricos que adquiri ao longo do
meu percurso académico, e é também sobre o crescimento enquanto futura profissional que
reflito ao longo do capítulo.
The following work represents the final stage of the Integrated Master's in Pharmaceutical Sciences, aiming to obtain the master’s degree and is divided into three chapters. The first chapter is entitled "Regulatory Framework of Cannabis sativa L. and its subproducts’ use in Cosmetic Products" and concerns the research work carried out on the use of Cannabis sativa L. and its subproducts in the cosmetic sector and the respective regulatory framework, under the guidance of Professor Ana Palmeira de Oliveira, PhD and co-guidance of Professor Rita Palmeira de Oliveira,PhD. Part of the work of this chapter was in line with the project “PAM4WELLNESS - Código da Operação: POCI-04—SIAC-2021-181319, Transferência do Conhecimento cientifico e tecnológico, COMPETE, Portugal2020”. The second chapter describes the professional experience gained during my internship at the Local Health Unit of Guarda, in hospital pharmacy, under the supervision of Carmo Teixeira, PharmD. Meanwhile, the third chapter recounts my professional experience in the field of community pharmacy, at Farmácia Ideal, under the supervision of Raquel Ramalheira, PharmD. The first chapter focus on the analysis and characterization of non-psychoactive Cannabis sativa L. compounds with interest in the cosmetic sector, providing an overview of its regulatory framework, especially in the European and US markets. The use of Cannabis sativa L. in society has been present for many centuries, with its use for recreational, medicinal purposes, and more recently in cosmetic products undergoing an evolutionary context worldwide, with periods of greater and lesser tolerance towards its use. For this work, it was initially important to characterize the plant and provide an evolutionary context to its consumption and use. It was understood that the interest in the plant and its subproducts is exponentially growing, leading to a more in-depth study of plant-based ingredients and their potential use in cosmetics. However, this use raises regulatory and scientific sustainability questions to ensure their safe use in cosmetic products. Currently, there is a significant gap in regulatory and legislative aspects among different markets, even within the European market and the United States of America. Nevertheless, it is expected that in the year 2024, a set of joint measures will be taken with the aim of harmonizing legislation worldwide and facilitating, based on credible scientific support, the response to consumers' needs. Through the study of these cosmetic ingredients based on Cannabis sativa L. and its subproducts, it has been possible to reflect on the positive impact they have shown for numerous skin conditions. The second chapter refers to the activities developed during my internship in Hospital Pharmacy, at Hospital Nossa Senhora da Assunção and Hospital Sousa Martins, which took place from March 27 to May 19, 2023. This chapter describes all the areas in which the hospital pharmacist operates and the context within the hospitals where I was involved. It is important to mention that I extensively describe all the processes inherent to the proper functioning of hospital pharmaceutical services and reflect on my learning during the internship and its significance in my education. The third chapter describes the activities I carried out at Farmácia Ideal from May 22 to August 14, 2023. Here, all the activities and processes necessary for the efficient development of tasks and responsibilities assigned to the pharmacist are reported. During this internship, I was able to consolidate much of the theoretical knowledge acquired throughout my academic path, and throughout the chapter I also did a reflection on personal and professional growth as a future pharmacist.
The following work represents the final stage of the Integrated Master's in Pharmaceutical Sciences, aiming to obtain the master’s degree and is divided into three chapters. The first chapter is entitled "Regulatory Framework of Cannabis sativa L. and its subproducts’ use in Cosmetic Products" and concerns the research work carried out on the use of Cannabis sativa L. and its subproducts in the cosmetic sector and the respective regulatory framework, under the guidance of Professor Ana Palmeira de Oliveira, PhD and co-guidance of Professor Rita Palmeira de Oliveira,PhD. Part of the work of this chapter was in line with the project “PAM4WELLNESS - Código da Operação: POCI-04—SIAC-2021-181319, Transferência do Conhecimento cientifico e tecnológico, COMPETE, Portugal2020”. The second chapter describes the professional experience gained during my internship at the Local Health Unit of Guarda, in hospital pharmacy, under the supervision of Carmo Teixeira, PharmD. Meanwhile, the third chapter recounts my professional experience in the field of community pharmacy, at Farmácia Ideal, under the supervision of Raquel Ramalheira, PharmD. The first chapter focus on the analysis and characterization of non-psychoactive Cannabis sativa L. compounds with interest in the cosmetic sector, providing an overview of its regulatory framework, especially in the European and US markets. The use of Cannabis sativa L. in society has been present for many centuries, with its use for recreational, medicinal purposes, and more recently in cosmetic products undergoing an evolutionary context worldwide, with periods of greater and lesser tolerance towards its use. For this work, it was initially important to characterize the plant and provide an evolutionary context to its consumption and use. It was understood that the interest in the plant and its subproducts is exponentially growing, leading to a more in-depth study of plant-based ingredients and their potential use in cosmetics. However, this use raises regulatory and scientific sustainability questions to ensure their safe use in cosmetic products. Currently, there is a significant gap in regulatory and legislative aspects among different markets, even within the European market and the United States of America. Nevertheless, it is expected that in the year 2024, a set of joint measures will be taken with the aim of harmonizing legislation worldwide and facilitating, based on credible scientific support, the response to consumers' needs. Through the study of these cosmetic ingredients based on Cannabis sativa L. and its subproducts, it has been possible to reflect on the positive impact they have shown for numerous skin conditions. The second chapter refers to the activities developed during my internship in Hospital Pharmacy, at Hospital Nossa Senhora da Assunção and Hospital Sousa Martins, which took place from March 27 to May 19, 2023. This chapter describes all the areas in which the hospital pharmacist operates and the context within the hospitals where I was involved. It is important to mention that I extensively describe all the processes inherent to the proper functioning of hospital pharmaceutical services and reflect on my learning during the internship and its significance in my education. The third chapter describes the activities I carried out at Farmácia Ideal from May 22 to August 14, 2023. Here, all the activities and processes necessary for the efficient development of tasks and responsibilities assigned to the pharmacist are reported. During this internship, I was able to consolidate much of the theoretical knowledge acquired throughout my academic path, and throughout the chapter I also did a reflection on personal and professional growth as a future pharmacist.
Description
Keywords
Cannabinoids Cannabissatival. Cbd Communitypharmacy Cosmetcs Cosmeticspro
Ducts Europe Hospitalpharmacy Legislation Portugal Regulatoryaffairs Regulatoryframework Usa