| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 2.25 MB | Adobe PDF |
Abstract(s)
Introdução: A palavra âhumorâ surgiu no passado, derivada da âTeoria Humoralâ de HipĂłcrates, pai da Medicina (1,2). O humor e o riso sĂŁo, desde a antiguidade, temas fracturantes. Devido Ă sua importĂąncia, complexidade e relevĂąncia histĂłrica, o riso foi abordado em diferentes ĂĄreas por diversos pensadores e escritores, como Umberto Eco (3). O grande inspirador e pioneiro nos benefĂcios terapĂȘuticos do humor, foi Norman Cousins (4). Esta dissertação centra-se nestes benefĂcios provocados pelo humor e pelo riso, no sistema endĂłcrino, tegumentar, reprodutor e cardiovascular. Os estudos foram realizados em indivĂduos saudĂĄveis e com patologia: eczema atĂłpico, diabetes mellitus tipo 2 e infertilidade. Pretende-se uma revisĂŁo sistemĂĄtica para avaliar cientificamente, os benefĂcios terapĂȘuticos do humor.
MĂ©todos: Foram pesquisadas publicaçÔes indexadas nas bases electrĂłnicas cientĂficas, Pubmed, B-On, Elsevier, ScienceDirect. Das 218 publicaçÔes identificadas, foram seleccionadas 10 para anĂĄlise.
Resultados: Doentes com eczema atĂłpico mostraram significativa diminuição da produção de IgE pelas cĂ©lulas B seminais cultivadas com espermatozĂłides e a expressĂŁo de galectina-3 nos espermatozĂłides foi reduzida. Os nĂveis de peptĂdeo derivado da dermicidina aumentaram sem afectar os nĂveis de proteĂna total no suor. Em mĂŁes saudĂĄveis e com EA, os nĂveis de melatonina no leite materno aumentaram e as reacçÔes alĂ©rgicas ao latĂ©x e a ĂĄcaros diminuĂram nas crianças alimentadas com leite materno apĂłs ambas as mĂŁes se rirem antes da amamentação.
Doentes com diabetes mellitus tipo 2 tiveram uma diminuição do nĂvel de prĂł-renina no sangue e uma regulação crescente do gene receptor da prĂł-renina, assim como uma supressĂŁo do aumento da glucose sanguĂnea pĂłs-prandial 2 horas apĂłs a refeição.
Em doentes inférteis, verificou-se que a taxa de gravidez aumentou.
Em indivĂduos saudĂĄveis, houve um maior gasto de energia e um aumento da frequĂȘncia cardĂaca existindo uma correlação entre eles e deles com a duração do riso. Verificou-se tambĂ©m um aumento dos valores da capacidade de eliminação de radicais livres na saliva. HĂĄ um aumento da pressĂŁo arterial, da vasodilatação da artĂ©ria braquial mediada por fluxo induzido por isquĂ©mia, da complacĂȘncia da artĂ©ria carĂłtida apesar de voltar ao estado basal apĂłs 24 horas. Observou-se em idosos que o fluxo salivar aumentou e em jovens os nĂveis de CgA diminuiram.
ConclusĂŁo: Este estudo leva-nos a supor que o humor e o riso apresentam benefĂcios terapĂȘuticos em indivĂduos saudĂĄveis e com patologia, nomeadamente eczema atĂłpico, diabetes mellitus tipo 2 e infertilidade, demonstrando a abrangĂȘncia de efeitos benĂ©ficos nos sistemas endĂłcrino, tegumentar, reprodutor e cardiovascular.
Introduction: The word "humor" has emerged in the past, derived from the "Humoral Theory" of Hippocrates, father of medicine (1,2). Humour and laughter are divisive issues, from ancient times. Due to its importance, complexity and historical significance, the laughter was approached in different areas by different thinkers and writers such as Umberto Eco (3). The great motivational and pioneer in the therapeutic benefits of humor, was Norman Cousins (4). This dissertation focuses on these benefits caused by the humor and laughter, in endocrine, cutaneous, reproductive and cardiovascular systems. The studies were performed in healthy subjects and patients with disease: atopic eczema, type 2 diabetes and infertility. The aim is a systematic review to scientifically evaluate the therapeutic benefits of humor. Methods: Indexed scientific publications were searched in electronic databases, Pubmed, B-On, Elsevier ScienceDirect. Among the 218 identified publications, 10 were selected for analysis. Results: Patients with atopic eczema showed a significant decrease of IgE production by B cells cultured with sperms and expression of galectin -3 on sperms was reduced. The levels of dermcidin-derived peptides increased without affecting total protein levels in sweat. In healthy mothers and with AE, levels of breast-milk melatonin increased and allergic reactions to latex and HDM decreased in infants fed by breast-milk after both mothers laugh before breastfeeding. Patients with type 2 diabetes mellitus have decreased the level of blood prorenin and up-regulation of the prorenin receptor gene as well as a suppression of increase of postprandial blood glucose 2 hours after meal. In infertile patients, it was found that the pregnancy rate increased. In healthy subjects, there was a greater energy expenditure and increased heart rate existing a correlation between them and of them with the duration of the laughter. There was also an increase in the values of the free radical-scavenging capacity in the saliva. There is an increase in blood pressure, ischemia-induced brachial artery flow-mediated vasodilation, carotid arterial compliance despite returning to baseline after 24 hours. It was observed in the elderly the salivary flow rates increased and in young, salivary CgA declined. Conclusion: This study leads us to assume that humor and laughter have therapeutic benefits in healthy individuals and those with disease, such as atopic eczema, diabetes mellitus type 2 and infertility, demonstrating the range of beneficial effects on the endocrine, cutaneous, reproductive and cardiovascular systems.
Introduction: The word "humor" has emerged in the past, derived from the "Humoral Theory" of Hippocrates, father of medicine (1,2). Humour and laughter are divisive issues, from ancient times. Due to its importance, complexity and historical significance, the laughter was approached in different areas by different thinkers and writers such as Umberto Eco (3). The great motivational and pioneer in the therapeutic benefits of humor, was Norman Cousins (4). This dissertation focuses on these benefits caused by the humor and laughter, in endocrine, cutaneous, reproductive and cardiovascular systems. The studies were performed in healthy subjects and patients with disease: atopic eczema, type 2 diabetes and infertility. The aim is a systematic review to scientifically evaluate the therapeutic benefits of humor. Methods: Indexed scientific publications were searched in electronic databases, Pubmed, B-On, Elsevier ScienceDirect. Among the 218 identified publications, 10 were selected for analysis. Results: Patients with atopic eczema showed a significant decrease of IgE production by B cells cultured with sperms and expression of galectin -3 on sperms was reduced. The levels of dermcidin-derived peptides increased without affecting total protein levels in sweat. In healthy mothers and with AE, levels of breast-milk melatonin increased and allergic reactions to latex and HDM decreased in infants fed by breast-milk after both mothers laugh before breastfeeding. Patients with type 2 diabetes mellitus have decreased the level of blood prorenin and up-regulation of the prorenin receptor gene as well as a suppression of increase of postprandial blood glucose 2 hours after meal. In infertile patients, it was found that the pregnancy rate increased. In healthy subjects, there was a greater energy expenditure and increased heart rate existing a correlation between them and of them with the duration of the laughter. There was also an increase in the values of the free radical-scavenging capacity in the saliva. There is an increase in blood pressure, ischemia-induced brachial artery flow-mediated vasodilation, carotid arterial compliance despite returning to baseline after 24 hours. It was observed in the elderly the salivary flow rates increased and in young, salivary CgA declined. Conclusion: This study leads us to assume that humor and laughter have therapeutic benefits in healthy individuals and those with disease, such as atopic eczema, diabetes mellitus type 2 and infertility, demonstrating the range of beneficial effects on the endocrine, cutaneous, reproductive and cardiovascular systems.
Description
Keywords
BenefĂcios Humor Medicina Riso Terapia