Characterization of the Mechanical and Biological Properties of a New Alumina Scaffold

Batista, Patrícia Sofia Pinhanços; Rodrigues, Miguel; Silva, Daniela; Morgado, Patrícia I.; Henriques, J.; Almeida, Maria; Silva, Abílio P.; Correia, Ilídio Joaquim Sobreira

http://hdl.handle.net/10400.6/4635

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Authors

Batista, Patrícia Sofia Pinhanços

Correia, Ilídio Joaquim Sobreira

Abstract(s)

Purpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: the results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. the in vivo studies revealed no systemic reaction. Conclusions: the alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.

Keywords

Alumina scaffolds Biomedical applications Bone regeneration Ceramic biomaterials Porosity Sintering

URI

http://hdl.handle.net/10400.6/4635

Citation

Batista, P., Rodrigues, M., Silva, D., Morgado, P.I., Henriques, J.P., Almeida, M.O., Silva, A.P. e Correia, I.J. (2013) "Characterization of the mechanical and biological properties of a new alumina scaffold", Journal of Applied Biomaterials and Functional Materials, Vol. 11(1), pp. e18-25