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Abstract(s)
Introdução: A Epilepsia Ă© uma patologia neurolĂłgica crĂłnica com grandes repercussĂ”es em termos de qualidade de vida para o doente. A sua prevalĂȘncia e perfil epidemiolĂłgico variam bastante entre as vĂĄrias regiĂ”es do mundo, nĂŁo apenas devido Ă s diversas etiologias, mas tambĂ©m devido aos diferentes mĂ©todos de investigação. Este estudo tem por objetivo determinar a PrevalĂȘncia e Perfil EpidemiolĂłgico de Epilepsia na população da Cova da Beira a 31 de dezembro de 2012 e, posteriormente, comparar os resultados com os disponĂveis na literatura, nĂŁo existindo nenhum estudo realizado em Portugal neste Ăąmbito.
Materiais e MĂ©todos: A identificação dos pacientes foi feita atravĂ©s da revisĂŁo dos doentes referenciados para realização de Eletroencefalograma no LaboratĂłrio de Eletrofisiologia do Centro Hospitalar da Cova da Beira complementada pela listagem de pacientes fornecido pelo Gabinete de Informação desse mesmo hospital com diagnĂłstico de Epilepsia pelo ICD-9, ambos no perĂodo compreendido entre 1 de janeiro de 2008 e 31 de dezembro de 2012. Posteriormente foram revistos todos os processos eletrĂłnicos dos doentes.
Resultados: A prevalĂȘncia de Epilepsia na população da Cova da Beira foi de 3,38 casos/ 1000 habitantes. A prevalĂȘncia foi ligeiramente superior em indivĂduos do sexo masculino. A faixa etĂĄria com prevalĂȘncia superior foi a dos 0 aos 20 anos de idade, de 4,45 casos/ 1000 habitantes. O grupo populacional com prevalĂȘncia especĂfica para idade mais elevada foi no sexo masculino dos 0 aos 20 anos, de 5,01 casos/ 1000 habitantes. Crises parciais foram encontradas numa percentagem superior de pacientes (48,6%) relativamente a outros tipos de crises, sendo o tipo mais frequente as crises parciais secundariamente generalizadas. A etiologia mais frequente foi a SintomĂĄtica, em 51% dos pacientes, estando os DistĂșrbios Cerebrovasculares e Traumatismos CrĂąneo-EncefĂĄlicos na base da maioria dos casos. Foi possĂvel identificar diagnĂłsticos sindrĂłmicos em 17,9% dos pacientes, sendo que as sĂndromes mais frequentes foram a Epilepsia RolĂąndica Benigna e a Epilepsia MioclĂłnica Juvenil. De toda a população epilĂ©tica, 14,1% nĂŁo fazia medicação, e 26,2% da população fazia mais do que um fĂĄrmaco antiepilĂ©tico. Dos pacientes que faziam monoterapia, o Ăcido ValprĂłico era o medicamento mais prescrito.
ConclusĂŁo: Todos os achados sĂŁo consistentes com os relatados noutros estudos, Ă exceção da baixa prevalĂȘncia detetada em indivĂduos com idade superior a 60 anos, de 2,53 casos/ 1000 habitantes. A PrevalĂȘncia Ă© similar Ă encontrada em estudos mais recentes realizados na Europa, mas inferior a paĂses AsiĂĄticos e Africanos.
Introduction: Epilepsy is a chronic neurological disease which has vast repercussions on the patientâs quality of life. Its prevalence and epidemiological profile varies greatly amongst the various regions of the world, not only because of the diverse etiologies it might have, but also due to the different methodologies used in the investigation. This study aims to determine the Prevalence and Epidemiological Profile of Epilepsy in the population of Cova da Beira on 31st of December 2012 and, thereafter, compare it with some international studies. There is no Portuguese study available on the subject so far. Material and Methods: The identification of the patients was made by review of referrals to the electroencephalographic facilities in Centro Hospitalar da Cova da Beira, and supplemented by the list of patients with the diagnose of Epilepsy through codification by ICD-9 provided by the Information Office, both between 1st of January 2008 and 31st of December 2012. Afterwards, all the electronic patient records were revised. Results: Prevalence of Epilepsy was 3,38 cases/ 1000. Prevalence was slightly higher in male subjects. The highest age-specific prevalence was found in patients aged 0 to 20 years old, 4,45 cases/ 1000. The group with the higher age-adjusted prevalence was male subjects aged 0 to 20 years (5,01 cases/1000). Partial seizures were found in a superior percentage of patients (48,6%) when compared with other types of seizures, being partial seizures with secondary generalization the most common. The most frequent etiology was the Symptomatic, in 51% of the patients, being cerebrovascular diseases and head trauma the causes of most of them. Syndromic diagnosis was possible in 17,9% of the patients â the most common was Benign Rolandic Epilepsy and Juvenile Myoclonic Epilepsy. Amongst all the epileptics, 14,1% did not do any drug, and 26,2% of the population did polytherapy. Among the patients who did monotherapy, Valproic Acid was the most prescript drug. Conclusion: All the findings are consistent with the reported in other studies, except the low prevalence found in patients aged 60 or over, of 2,53 cases/ 1000. The prevalence is similar to European studies, but lower than that reported in Asia and Africa.
Introduction: Epilepsy is a chronic neurological disease which has vast repercussions on the patientâs quality of life. Its prevalence and epidemiological profile varies greatly amongst the various regions of the world, not only because of the diverse etiologies it might have, but also due to the different methodologies used in the investigation. This study aims to determine the Prevalence and Epidemiological Profile of Epilepsy in the population of Cova da Beira on 31st of December 2012 and, thereafter, compare it with some international studies. There is no Portuguese study available on the subject so far. Material and Methods: The identification of the patients was made by review of referrals to the electroencephalographic facilities in Centro Hospitalar da Cova da Beira, and supplemented by the list of patients with the diagnose of Epilepsy through codification by ICD-9 provided by the Information Office, both between 1st of January 2008 and 31st of December 2012. Afterwards, all the electronic patient records were revised. Results: Prevalence of Epilepsy was 3,38 cases/ 1000. Prevalence was slightly higher in male subjects. The highest age-specific prevalence was found in patients aged 0 to 20 years old, 4,45 cases/ 1000. The group with the higher age-adjusted prevalence was male subjects aged 0 to 20 years (5,01 cases/1000). Partial seizures were found in a superior percentage of patients (48,6%) when compared with other types of seizures, being partial seizures with secondary generalization the most common. The most frequent etiology was the Symptomatic, in 51% of the patients, being cerebrovascular diseases and head trauma the causes of most of them. Syndromic diagnosis was possible in 17,9% of the patients â the most common was Benign Rolandic Epilepsy and Juvenile Myoclonic Epilepsy. Amongst all the epileptics, 14,1% did not do any drug, and 26,2% of the population did polytherapy. Among the patients who did monotherapy, Valproic Acid was the most prescript drug. Conclusion: All the findings are consistent with the reported in other studies, except the low prevalence found in patients aged 60 or over, of 2,53 cases/ 1000. The prevalence is similar to European studies, but lower than that reported in Asia and Africa.
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Keywords
Eletroencefalograma Epidemiologia Epilepsia FĂĄrmacos AntiepilĂ©ticos SĂndromes EpilĂ©ticos