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Abstract(s)
O presente trabalho encontra-se dividido em três capítulos. Cada capítulo corresponde à experiencia profissionalizante adquirida nas diferentes áreas nomeadamente na componente de Farmácia Hospitalar, Farmácia Comunitária e Investigação.
O primeiro capítulo deste trabalho pretende descrever a experiencia profissional em Farmácia Hospitalar, no Centro Hospitalar Cova da Beira, assim como elucidar todas as competências técnico-científicas adquiridas, atividades desenvolvidas e metodologias observadas durante o estágio.
O Segundo capítulo tem como objetivo descrever as atividades desenvolvidas e a experiência adquirida ao longo do estágio em Farmácia Comunitária, na Farmácia S. Cosme, evidenciando o funcionamento da mesma e o papel do farmacêutico comunitário nesta área.
Por fim, o último capítulo deste relatório relacionado com a vertente de investigação pretende descrever o projeto desenvolvido. O objetivo deste trabalho consiste na obtenção de um material têxtil de algodão funcionalizado com péptido antimicrobiano, Cys-LC-LL-37, para obtenção de um efeito antibacteriano, com potencial aplicação em materiais têxteis biomédicos, geriátricos e pediátricos. Os resultados obtidos neste trabalho revelaram que este processo confere bioatividade ao material tratado, traduzida através de efeito antibacteriano em bactérias Gram positivas e Gram negativas, avaliado pela norma JIS L 1902-2002, com efeito permanente comprovado através dos ensaios da avaliação da eficácia da funcionalização.
The present work is divided into three chapters. Each chapter corresponds to the professional experience acquired in the areas of Hospital Pharmacy, Community Pharmacy, and Research, respectively. The first chapter of the work aims to describe the professional experience in Hospital Pharmacy, at Hospital Cova da Beira, as all technical and scientific skills acquired, activities and methodologies that were observed during the internship. The second chapter aims to describe the activities and experience gained during the internship in Community Pharmacy, at Pharmacy S. Cosme, showing it’s operation, and the role of the pharmacist in this area. Finally, the last chapter of the report, concerning the research experience, aims to describe the project developed. The purpose of this work is to obtain a cotton textile material functionalized with antimicrobial peptide, Cys-LC-LL-37 to achieve an antimicrobial effect with potential application in biomedical, geriatric and pediatric textiles. The results of this study reveal that this process confers bioactivity to the treated fabric, represented by antibacterial effect on Gram positive and Gram negative bacteria, measured by JIS L 1902- 2002, with permanent effect demonstrated through assays evaluating the effectiveness of the functionalisation.
The present work is divided into three chapters. Each chapter corresponds to the professional experience acquired in the areas of Hospital Pharmacy, Community Pharmacy, and Research, respectively. The first chapter of the work aims to describe the professional experience in Hospital Pharmacy, at Hospital Cova da Beira, as all technical and scientific skills acquired, activities and methodologies that were observed during the internship. The second chapter aims to describe the activities and experience gained during the internship in Community Pharmacy, at Pharmacy S. Cosme, showing it’s operation, and the role of the pharmacist in this area. Finally, the last chapter of the report, concerning the research experience, aims to describe the project developed. The purpose of this work is to obtain a cotton textile material functionalized with antimicrobial peptide, Cys-LC-LL-37 to achieve an antimicrobial effect with potential application in biomedical, geriatric and pediatric textiles. The results of this study reveal that this process confers bioactivity to the treated fabric, represented by antibacterial effect on Gram positive and Gram negative bacteria, measured by JIS L 1902- 2002, with permanent effect demonstrated through assays evaluating the effectiveness of the functionalisation.
Description
Keywords
Péptidos antimicrobianos Materiais têxteis Funcionalização de materiais Têxteis técnicos e funcionais