| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 1.38 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
Introdução: Ao longo da história da humanidade, a planta Cannabis tem sido
utilizada com finalidade médica, possuindo uma panóplia de ações benéficas bem
conhecidas, nomeadamente relacionadas com a neuroprotecção.
A Doença de Parkinson é uma doença neurodegenerativa altamente complexa e
condicionante de uma grande carga de doença, sendo o seu tratamento atual paliativo e
limitado. A demanda de novos fármacos culminou no crescente interesse no
desenvolvimento de novos tratamentos direcionados a sistemas não dopaminérgicos,
nomeadamente o Sistema Endocanabinóide.
Metodologia: A propósito da elaboração da presente monografia, foi efetuada uma
pesquisa bibliográfica recorrendo a diferentes bases de dados como a PubMed,
Cochrane, ScienceDirect e Medscape, tendo sido também consultados alguns livros de
referência.
Objetivo: O objetivo deste trabalho passa por averiguar o estado da arte no que
concerne aos efeitos dos canabinóides e seu potencial terapêutico na Doença de
Parkinson esporádica.
Conclusão: A utilização de canabinóides na Doença de Parkinson não é, atualmente,
uma realidade, apesar de ser inegável o seu potencial. Acredita-se que poderá, no
futuro, ser uma alternativa viável ou adição pertinente ao atual tratamento da Doença
de Parkinson.
Introduction: Throughout human history, the Cannabis plant has been used for medical purposes, since it possesses a panoply of well-known beneficial actions, namely neuroprotection related. Parkinson's disease is a highly complex neurodegenerative disease with a high burden of disease, which current treatment is limited and mainly palliative. Thus, the rising demand for new pharmacological treatments lead to the growing interest in the development of new treatments aimed at non-dopaminergic systems, namely the Endocannabinoid System. Methodology: Regarding the elaboration of this paper, bibliographic research was conducted by consulting different databases such as PubMed, Cochrane, ScienceDirect and Medscape, as well as some reference books. Objective: The aim of this monograph is to investigate the state of the art regarding the effects of cannabinoids and their therapeutic potential in sporadic Parkinson's disease. Conclusion: The use of cannabinoids in Parkinson's disease is not currently a reality, although its potential is undeniable. However, it is reasonable to expect that, in the future, it may be a viable alternative or relevant addition to the current treatment of Parkinson's disease.
Introduction: Throughout human history, the Cannabis plant has been used for medical purposes, since it possesses a panoply of well-known beneficial actions, namely neuroprotection related. Parkinson's disease is a highly complex neurodegenerative disease with a high burden of disease, which current treatment is limited and mainly palliative. Thus, the rising demand for new pharmacological treatments lead to the growing interest in the development of new treatments aimed at non-dopaminergic systems, namely the Endocannabinoid System. Methodology: Regarding the elaboration of this paper, bibliographic research was conducted by consulting different databases such as PubMed, Cochrane, ScienceDirect and Medscape, as well as some reference books. Objective: The aim of this monograph is to investigate the state of the art regarding the effects of cannabinoids and their therapeutic potential in sporadic Parkinson's disease. Conclusion: The use of cannabinoids in Parkinson's disease is not currently a reality, although its potential is undeniable. However, it is reasonable to expect that, in the future, it may be a viable alternative or relevant addition to the current treatment of Parkinson's disease.
Description
Keywords
Cannabis and Cannabinoids Cannabis and Parkinson'S Disease Endocannabinoid System Endocannabinoid System and Parkinson Parkinson'S Disease