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Abstract(s)
O presente relatório de estágio para obtenção do grau de Mestre em Ciências
Farmacêuticas encontra-se dividido em três capítulos. O primeiro é referente à vertente
de Investigação, o segundo à experiência profissionalizante em Farmácia Comunitária e
o último à experiência de estágio em Farmácia Hospitalar.
O primeiro capítulo teve como objetivo estudar a eficácia dos medicamentos à base de
canábis na redução da espasticidade associada à esclerose múltipla. Foi realizada uma
revisão da literatura, sendo incluídos os estudos que reportassem o uso destes fármacos
no tratamento sintomático da espasticidade e aplicassem um método quantitativo de
avaliação da sua eficácia. Foram identificados 9 estudos que cumpriram com os
critérios de inclusão definidos, tendo sido analisados os seus resultados. Estabeleceu-se
que os medicamentos à base de canábis são eficazes no tratamento da espasticidade
associada à esclerose múltipla, sendo reportadas melhorias no sintoma e na qualidade
de vida dos doentes, através da aplicação de escalas quantitativas. No futuro, espera-se
que surjam novos estudos que comprovem esta eficácia através da aplicação de escalas
quantitativas e clínicas, minimizando o viés e subjetividade associados.
No segundo capítulo são relatadas todas as atividades desenvolvidas no âmbito do
Estágio Curricular em Farmácia Comunitária, desenvolvido na Farmácia Social da
Associação Mutualista da Covilhã (Mutualista Covilhanense) entre 21 de setembro de
2020 e 27 de novembro do mesmo ano civil. No terceiro capítulo serão descritas as
atividades referentes ao Estágio Curricular em Farmácia Hospitalar, que decorreu no
Centro Hospitalar Universitário da Cova da Beira entre 4 de dezembro de 2020 e 29 de
janeiro de 2021.
This dissertation is an integral part of the “Internship” curricular unit of the Integrated Master’s Degree in Pharmaceutical Sciences. It is divided into three different chapters. The first chapter refers to the research section, and in the second and third chapters the activities concerning the internships in Community and Hospital Pharmacy are described. The study presented in chapter I aimed to investigate the effectiveness of cannabis drugs in reducing spasticity associated with multiple sclerosis (MS). A review of the literature was conducted, and studies were included if they reported the use of cannabis drugs to treat MS-related spasticity and applied a quantitative measuring scale. The review identified 9 studies that met the inclusion criteria, and the results were analyzed. The findings indicated that cannabis drugs are effective in reducing spasticity associated with MS, with reports of improved patients' subjective ratings of spasticity and quality of life. However, further research is needed to establish the effectiveness in association with other forms of measure, mainly clinical measuring scales. In chapter II, the activities regarding a curricular internship in a Community Pharmacy are described, which took place at Farmácia Social da Associação Mutualista in Covilhã (Mutualista Covilhanense) between the 21st of September and 27th of November of 2020. In chapter III are described the activities concerning a curricular internship in the Hospital Pharmacy Services of Centro Hospitalar Universitário da Cova da Beira, which took place between the 4th of December of 2020 and the 29th of January of 2021.
This dissertation is an integral part of the “Internship” curricular unit of the Integrated Master’s Degree in Pharmaceutical Sciences. It is divided into three different chapters. The first chapter refers to the research section, and in the second and third chapters the activities concerning the internships in Community and Hospital Pharmacy are described. The study presented in chapter I aimed to investigate the effectiveness of cannabis drugs in reducing spasticity associated with multiple sclerosis (MS). A review of the literature was conducted, and studies were included if they reported the use of cannabis drugs to treat MS-related spasticity and applied a quantitative measuring scale. The review identified 9 studies that met the inclusion criteria, and the results were analyzed. The findings indicated that cannabis drugs are effective in reducing spasticity associated with MS, with reports of improved patients' subjective ratings of spasticity and quality of life. However, further research is needed to establish the effectiveness in association with other forms of measure, mainly clinical measuring scales. In chapter II, the activities regarding a curricular internship in a Community Pharmacy are described, which took place at Farmácia Social da Associação Mutualista in Covilhã (Mutualista Covilhanense) between the 21st of September and 27th of November of 2020. In chapter III are described the activities concerning a curricular internship in the Hospital Pharmacy Services of Centro Hospitalar Universitário da Cova da Beira, which took place between the 4th of December of 2020 and the 29th of January of 2021.
Description
Keywords
Canabidiol Canábis Cannabis para Uso Medicinal Esclerose Múltipla Espasticidade Farmácia Comunitária Farmácia Hospitalar Tetrahidrocanabinol