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Compostos Fenólicos: uma Estratégia Natural para um Envelhecimento Saudável
| Name: | Description: | Size: | Format: | |
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| 1.65 MB | Adobe PDF |
Advisor(s)
Abstract(s)
O presente relatório, realizado no âmbito da Unidade curricular de Estágio para a obtenção
do grau de Mestre em Ciências Farmacêuticas, divide-se em 3 capítulos. O primeiro capítulo
é uma revisão bibliográfica, alusivo à área de investigação. O segundo capítulo corresponde
ao relatório de estágio em farmácia comunitária e o terceiro capítulo, ao relatório de estágio
em farmácia hospitalar.
O primeiro capítulo aborda o potencial dos Compostos Fenólicos enquanto estratégia
natural para um envelhecimento saudável. É notável que a percentagem da população idosa
tem vindo a aumentar a nível global, tornando o envelhecimento um tópico de interesse
para a sociedade. Apesar de ser um processo natural, o envelhecimento é um dos maiores
fatores de risco para doenças crónicas, como as cardiovasculares, neurodegenerativas e
dermatológicas. Deste modo, há cada vez mais interesse na procura de novas estratégias
que melhorem a qualidade de vida das populações idosas. Nesta revisão, os compostos
fenólicos foram explorados quanto à sua classificação, às respetivas fontes e quanto às
principais funções e benefícios no envelhecimento. Analisando a literatura disponível na
base de dados do PubMed, foram selecionados vários estudos in vitro, in vivo e ensaios
clínicos que evidenciaram a atividade antioxidante dos compostos fenólicos, os efeitos
cardioprotetores, os benefícios na doença de Alzheimer e no antienvelhecimento da pele.
Todos estes efeitos, apontam os compostos fenólicos como uma potencial estratégia no
combate ao envelhecimento e na melhoria da qualidade de vida da população idosa.
O segundo capítulo reúne as competências obtidas durante o estágio curricular em farmácia
comunitária, realizado na Farmácia Neves Ferreira, em Celorico de Basto. O período de
estágio iniciou a 5 de fevereiro e terminou a 24 de abril de 2024, durante o qual se
possibilitou compreender aquilo que é a prática profissional diária e as responsabilidades
do farmacêutico comunitário.
Por fim, o terceiro capítulo corresponde ao relatório de estágio curricular em farmácia
hospitalar, que se realizou nos serviços farmacêuticos da ULS Cova da Beira, na Covilhã,
desde o dia 29 de abril até ao dia 21 de junho de 2024. Neste capítulo, são mencionadas as
várias atividades realizadas no papel de estagiária, bem como as responsabilidades e
funções que competem ao farmacêutico hospitalar.
The present report, conducted as part of the Internship curricular unit for the completion of the master’s degree in Pharmaceutical Sciences, is divided into three chapters. The first chapter consists of a literature review related to the research area. The second chapter presents the internship report from the community pharmacy, and the third chapter includes the hospital pharmacy internship report. The first chapter explores the potential of phenolic compounds as a natural strategy for healthy aging. The percentage of the aging population has been increasing globally, making aging an important topic for society. Although it is a natural process, aging is one of the main risk factors for chronic diseases, such as cardiovascular, neurodegenerative, and dermatological conditions. Therefore, there is growing interest in identifying new strategies to improve the quality of life of the aging population. This review examines phenolic compounds in terms of their classification, sources, and key functions and benefits in aging. Based on literature available in the PubMed database, several in vitro, in vivo, and clinical studies were selected, highlighting the antioxidant activity of phenolic compounds, their cardioprotective effects, and their benefits in Alzheimer’s disease and skin aging. These findings suggest that phenolic compounds may represent a promising strategy to combat aging and improve the quality of life of the aging population. The second chapter presents the skills acquired during the community pharmacy internship, conducted at Farmácia Neves Ferreira in Celorico de Basto. The internship took place from February 5 to April 24, 2024, providing an opportunity to understand daily professional practice and the responsibilities of a community pharmacist. Finally, the third chapter describes the hospital pharmacy internship, which was carried out at the Pharmaceutical Services of ULS Cova da Beira, in Covilhã, from April 29 to June 21, 2024. This chapter outlines the various activities performed as an intern, as well as the responsibilities and roles of a hospital pharmacist.
The present report, conducted as part of the Internship curricular unit for the completion of the master’s degree in Pharmaceutical Sciences, is divided into three chapters. The first chapter consists of a literature review related to the research area. The second chapter presents the internship report from the community pharmacy, and the third chapter includes the hospital pharmacy internship report. The first chapter explores the potential of phenolic compounds as a natural strategy for healthy aging. The percentage of the aging population has been increasing globally, making aging an important topic for society. Although it is a natural process, aging is one of the main risk factors for chronic diseases, such as cardiovascular, neurodegenerative, and dermatological conditions. Therefore, there is growing interest in identifying new strategies to improve the quality of life of the aging population. This review examines phenolic compounds in terms of their classification, sources, and key functions and benefits in aging. Based on literature available in the PubMed database, several in vitro, in vivo, and clinical studies were selected, highlighting the antioxidant activity of phenolic compounds, their cardioprotective effects, and their benefits in Alzheimer’s disease and skin aging. These findings suggest that phenolic compounds may represent a promising strategy to combat aging and improve the quality of life of the aging population. The second chapter presents the skills acquired during the community pharmacy internship, conducted at Farmácia Neves Ferreira in Celorico de Basto. The internship took place from February 5 to April 24, 2024, providing an opportunity to understand daily professional practice and the responsibilities of a community pharmacist. Finally, the third chapter describes the hospital pharmacy internship, which was carried out at the Pharmaceutical Services of ULS Cova da Beira, in Covilhã, from April 29 to June 21, 2024. This chapter outlines the various activities performed as an intern, as well as the responsibilities and roles of a hospital pharmacist.
Description
Keywords
Doença de Alzheimer Compostos Fenólicos Doenças Cardiovasculares Envelhecimento Farmácia Comunitária Farmácia Hospitalar Pele Stress Oxidativo