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Abstract(s)
As doenças cardiovasculares representam uma preocupação global de saúde, sendo das
principais causas de morbidade e mortalidade a nível mundial.
A introdução na alimentação humana de prebióticos (substâncias não digeríveis que
estimulam o crescimento de bactérias benéficas já presentes na microbiota) e
probióticos (bactérias benéficas que melhoraram a composição da microbiota) têm
apresentado um impacto positivo na microbiota intestinal atuando através de diversos
mecanismos, desde a produção de metabolitos específicos até a modulação da sua
composição.
A disbiose, caracterizada pelo desequilíbrio na composição da microbiota, tem sido
associada a várias condições patológicas, incluindo doenças cardiovasculares. A
presença de bactérias patogénicas e a redução de espécies benéficas pode desencadear
processos inflamatórios crónicos e contribuir para a progressão da insuficiência
cardíaca, aterosclerose, doença arterial coronária e hipertensão arterial.
Os prebióticos e os probióticos parecem ter um impacto positivo na saúde
cardiovascular. Estes efeitos incluem uma redução do colesterol e melhoria no controlo
da pressão arterial, fatores de risco significativos para as doenças cardiovasculares.
Para além disso, por terem propriedades antioxidantes e anti-inflamatórias, poderão
ser benéficos na prevenção de eventos cardiovasculares.
No entanto, para se compreender melhor o impacto destes componentes na saúde
cardiovascular, é de extrema importância realizar mais estudos em humanos que
forneçam mais informações e comprovem a eficácia desta abordagem no tratamento e
prevenção das doenças cardiovasculares.
Em síntese, há interação entre a microbiota intestinal, os seus metabolitos e as doenças
cardiovasculares e os prebióticos e probióticos são possíveis aliados na promoção da
saúde cardiovascular. Integrar estratégias que visem equilibrar a microbiota poderá vir
a representar uma abordagem complementar no combate às doenças cardiovasculares,
proporcionando benefícios significativos à saúde humana.
Being one of the main causes of morbidity and mortality worldwide, cardiovascular diseases represent a global health concern. Introducing prebiotics (non-digestible substances that stimulate the growth of beneficial bacteria already present in the microbiota) and probiotics (beneficial bacteria that improve the composition of the microbiota) into human nutrition has proven to have a positive impact in the intestinal microbiota acting through different mechanisms, from the production of specific metabolites to the modulation of their composition. Known for unbalancing the composition of the microbiota, Disbiose, has been associated with several pathological conditions including cardiovascular diseases. The presence of pathogenic bacteria and the reduction of beneficial species can trigger chronic inflammatory processes and contribute to the progression of heart failure, atherosclerosis, coronary artery disease and high blood pressure. Prebiotics and probiotics appear to have a positive impact on cardiovascular health. This includes a reduction in cholesterol and improved blood pressure control, significant risk factors for cardiovascular diseases. Also, due to having antioxidant and anti-inflammatory properties, they may be also beneficial in preventing cardiovascular events. To better understand the impact of these components on cardiovascular health, is it then extremely important to carry out more studies to gather more information and help prove the effectiveness of this approach in the treatment and prevention of cardiovascular diseases. In summary, there is a connection between the intestinal microbiota, its metabolites, and cardiovascular diseases, where prebiotics and probiotics are possible allies in promoting cardiovascular health. Incorporate strategies that aim to balance the microbiota could represent a complementary approach in the fight against cardiovascular diseases, providing significant benefits to human health.
Being one of the main causes of morbidity and mortality worldwide, cardiovascular diseases represent a global health concern. Introducing prebiotics (non-digestible substances that stimulate the growth of beneficial bacteria already present in the microbiota) and probiotics (beneficial bacteria that improve the composition of the microbiota) into human nutrition has proven to have a positive impact in the intestinal microbiota acting through different mechanisms, from the production of specific metabolites to the modulation of their composition. Known for unbalancing the composition of the microbiota, Disbiose, has been associated with several pathological conditions including cardiovascular diseases. The presence of pathogenic bacteria and the reduction of beneficial species can trigger chronic inflammatory processes and contribute to the progression of heart failure, atherosclerosis, coronary artery disease and high blood pressure. Prebiotics and probiotics appear to have a positive impact on cardiovascular health. This includes a reduction in cholesterol and improved blood pressure control, significant risk factors for cardiovascular diseases. Also, due to having antioxidant and anti-inflammatory properties, they may be also beneficial in preventing cardiovascular events. To better understand the impact of these components on cardiovascular health, is it then extremely important to carry out more studies to gather more information and help prove the effectiveness of this approach in the treatment and prevention of cardiovascular diseases. In summary, there is a connection between the intestinal microbiota, its metabolites, and cardiovascular diseases, where prebiotics and probiotics are possible allies in promoting cardiovascular health. Incorporate strategies that aim to balance the microbiota could represent a complementary approach in the fight against cardiovascular diseases, providing significant benefits to human health.
Description
Keywords
Dislipidemia Doenças Cardiovasculares Hipertensão Arterial Microbiota Prebióticos Probióticos Simbióticos