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Authors
Abstract(s)
A presente dissertação está dividida em dois capítulos distintos. O primeiro capítulo, no qual é descrito o trabalho de investigação e estudo retrospetivo relativos à terapêutica farmacológica da pré-eclâmpsia e eclâmpsia, no Centro Hospitalar Cova da Beira, Covilhã. O segundo capítulo apresenta informação relativa à experiência adquirida no estágio curricular em farmácia comunitária.
O trabalho de investigação descrito no capítulo 1 é baseado num trabalho de revisão efetuado sobre a epidemiologia, patofisiologia e tratamento da pré-eclâmpsia e eclâmpsia. Estas duas doenças hipertensivas da gravidez são uma importante causa de mortalidade materna e perinatal a nível mundial. As medidas de prevenção atuais limitam-se ao ácido acetilsalicílico em doses baixas. Deste modo, é importante estabelecer qual o tratamento mais seguro e eficaz a administrar. Neste contexto, realizou-se um estudo retrospetivo, anonimizado, sobre a terapêutica farmacológica instituída no Centro Hospitalar Cova da Beira em mulheres diagnosticadas com as referidas doenças, no período de 1 de janeiro de 2015 a 31 de dezembro de 2016, de modo a estabelecer uma comparação com a terapêutica administrada neste hospital com as recomendações das mais recentes guidelines nacionais e internacionais. Foi verificado, para a pré-eclâmpsia leve, uma prevalência na administração de metildopa e nifedipina. No caso da pré-eclâmpsia grave, o labetalol é o fármaco de escolha, com a nifedipina a servir de alternativa. A prevenção da eclâmpsia é efetuada com sulfato de magnésio. Após o estudo retrospetivo, é possível concluir que o Centro Hospitalar Cova da Beira segue as recomendações de diversas guidelines abordadas neste trabalho de investigação.
O capítulo 2 deste trabalho relata o estágio realizado em farmácia comunitária, nomeadamente na Farmácia São João, na Covilhã. O relatório de estágio descreve todos os conhecimentos adquiridos ao longo das 800 horas de trabalho, englobando as áreas da farmácia relativas a: atendimento ao público, aconselhamento, dispensa de medicamentos, realização e receção de encomendas, outros serviços de saúde, faturação e legislação. O estágio permitiu-me perceber e familiarizar com as responsabilidades e contributos do farmacêutico na sociedade.
This dissertation is divided in two distinct chapters. The first chapter describes the investigation and retrospective cohort study about the pharmacological therapy in pre-eclampsia and eclampsia, in Centro Hospitalar Cova da Beira, in Covilhã. The second chapter presents information regarding the acquired experience in the curricular community pharmacy internship. The investigation work described in chapter one is based in a review on the epidemiology, pathophysiology and treatment of pre-eclampsia and eclampsia. These two hypertensive disorders of pregnancy are an important cause of maternal and perinatal death worldwide. Pharmacological prevention measures are limited to low dose aspirin. It is important to establish the safest and most effective treatment available. In this context, an anonymised retrospective cohort study was performed, regarding the pharmacological therapy given to women diagnosed with this diseases at Centro Hospitalar Cova da Beira, between the 1st of January 2015 and 31st of December 2016. The objective was to compare the drugs given at this hospital with the recommended therapies found in the most recent national and international guidelines for the quoted diseases. For moderate pre-eclampsia, it was found a prevalence in the use of methyldopa and nifedipine. In case of severe pre-eclampsia, it was found that the drug of choice was labetalol, being nifedipine the alternative. For the prevention of eclampsia, magnesium sulphate was the drug of choice. After this retrospective cohort study, it was concluded that Centro Hospitalar Cova da Beira follows the recommendations of some of the guidelines used in this investigation. The second chapter of this work describes the community pharmacy internship, held at Farmácia São João, in Covilhã. The report for this internship describes all the knowledge acquired during the 800 hours of work field, encompassing all the areas of the pharmacy regarding of: customer service, pharmaceutical counselling, drug dispensing, order fulfilment and receipt, other health services, invoices and legislation. This internship allowed me to understand and to get familiar with the pharmacist’s responsibilities and contribution in the society.
This dissertation is divided in two distinct chapters. The first chapter describes the investigation and retrospective cohort study about the pharmacological therapy in pre-eclampsia and eclampsia, in Centro Hospitalar Cova da Beira, in Covilhã. The second chapter presents information regarding the acquired experience in the curricular community pharmacy internship. The investigation work described in chapter one is based in a review on the epidemiology, pathophysiology and treatment of pre-eclampsia and eclampsia. These two hypertensive disorders of pregnancy are an important cause of maternal and perinatal death worldwide. Pharmacological prevention measures are limited to low dose aspirin. It is important to establish the safest and most effective treatment available. In this context, an anonymised retrospective cohort study was performed, regarding the pharmacological therapy given to women diagnosed with this diseases at Centro Hospitalar Cova da Beira, between the 1st of January 2015 and 31st of December 2016. The objective was to compare the drugs given at this hospital with the recommended therapies found in the most recent national and international guidelines for the quoted diseases. For moderate pre-eclampsia, it was found a prevalence in the use of methyldopa and nifedipine. In case of severe pre-eclampsia, it was found that the drug of choice was labetalol, being nifedipine the alternative. For the prevention of eclampsia, magnesium sulphate was the drug of choice. After this retrospective cohort study, it was concluded that Centro Hospitalar Cova da Beira follows the recommendations of some of the guidelines used in this investigation. The second chapter of this work describes the community pharmacy internship, held at Farmácia São João, in Covilhã. The report for this internship describes all the knowledge acquired during the 800 hours of work field, encompassing all the areas of the pharmacy regarding of: customer service, pharmaceutical counselling, drug dispensing, order fulfilment and receipt, other health services, invoices and legislation. This internship allowed me to understand and to get familiar with the pharmacist’s responsibilities and contribution in the society.
Description
Keywords
Eclâmpsia Estudo Retrospetivo Farmácia Comunitária Guidelines Pre-Eclâmpsia Revisão Terapêutica Farmacológica