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Effects of red clover on perimenopausal and postmenopausal women's blood lipid profile: A meta-analysis

2018Journal article Restricted access
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dc.contributor.authorLuís, Ângelo
dc.contributor.authorDomingues, F.C.
dc.contributor.authorPereira, L.
dc.date.accessioned2020-01-28T14:11:27Z
dc.date.available2020-01-28T14:11:27Z
dc.date.issued2018
dc.description.abstractThe study aimed to perform a systematic review with meta-analysis of randomized controlled trials (RCTs) to access the effects of red clover isoflavones on the blood lipid profile of both perimenopausal and postmenopausal women. PubMed, Web of Science, Scopus, SciELO, and Cochrane Library were searched for the terms 'red clover', 'Trifolium pratense', and 'randomized controlled trial' during November 2017. Summary measures were reported as weighted mean differences (WMD) with 95% confidence interval (CI). Fixed or random effects models were used for meta-analyses, according to heterogeneity. Risk of bias was measured with the Cochrane tool. Twelve RCTs (totalizing 1284 perimenopausal and postmenopausal women receiving red clover isoflavones for 4 weeks-18 months) resulted in a significant decrease in total cholesterol (WMD = -12.34 mg/dl; 95% CI: -18.21, -6.48), low-density lipoprotein cholesterol (WMD = -10.61 mg/dl; 95% CI: -15.51, -5.72), and triglycerides (WMD = -10.18 mg/dl; 95% CI: -16.23, -4.13) together with a significant increase in high-density lipoprotein cholesterol (WMD = 1.60 mg/dl; 95% CI: 0.17, 3.03). In conclusion, the results demonstrate that the ingestion of red clover may have a beneficial effect on the lipid profile of perimenopausal and postmenopausal women.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1080/13697137.2018.1501673pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.6/8809
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectRed cloverpt_PT
dc.subjectIsoflavonespt_PT
dc.subjectLipid profilept_PT
dc.subjectMenopausal womenpt_PT
dc.subjectMeta-analysispt_PT
dc.subjectSystematic reviewpt_PT
dc.titleEffects of red clover on perimenopausal and postmenopausal women's blood lipid profile: A meta-analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage453pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage446pt_PT
oaire.citation.titleClimactericpt_PT
oaire.citation.volume21pt_PT
person.familyNameLuís
person.familyNameDomingues
person.familyNamePereira
person.givenNameÂngelo Filipe Santos
person.givenNameFernanda
person.givenNameLuísa
person.identifier.ciencia-id3D14-798B-65D3
person.identifier.ciencia-id6514-0498-3E8F
person.identifier.ciencia-id4F15-1868-D001
person.identifier.orcid0000-0003-0712-6522
person.identifier.orcid0000-0002-9540-0853
person.identifier.orcid0000-0002-9068-4607
person.identifier.ridN-7295-2013
person.identifier.scopus-author-id10139481400
person.identifier.scopus-author-id10839238300
rcaap.embargofctCopyright cedido à editora no momento da publicaçãopt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa2d7c872-99db-41e1-9bc9-82c2d47b4661
relation.isAuthorOfPublication8d5fe6e2-21af-4557-9c46-84103254a18a
relation.isAuthorOfPublication604e508e-9f4e-4950-b2a4-1b06c7192afe
relation.isAuthorOfPublication.latestForDiscoverya2d7c872-99db-41e1-9bc9-82c2d47b4661

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