| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 855.34 KB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
No mundo atual, a prevalência da obesidade tem aumentado, sendo que a epidemiologia das doenças tem sofrido grandes alterações. Nesta sequência, verifica-se uma crescente incidência da Esteatose Hepática Não-Alcoólica. Esta doença varia desde a esteatose simples (com um curso maioritariamente benigno) até à esteato-hepatite não-alcoólica, que por sua vez pode evoluir para cirrose. Assim, é de interesse médico detetar precocemente a presença de esteato-hepatite não-alcoólica, de forma a prevenir posteriores complicações.
A biópsia hepática é o Gold standard para caracterização histológica. No entanto, sendo um meio invasivo e associado a diversas complicações, surge a necessidade de equacionar a utilização de outros meios complementares de diagnóstico, especialmente: ecografia hepática, tomografia computorizada sem contraste, elastografia hepática transitória, imagem de impulso da força de radiação acústica, espectroscopia por ressonância magnética e elastografia por ressonância magnética.
Esta revisão pretende analisar e comparar os meios diagnósticos anteriormente referidos, tendo especial atenção ao papel da elastografia hepática transitória na avaliação da esteatose hepática não-alcoólica, visto ser uma técnica relativamente recente e promissora.
In the world today, the prevalence of obesity has increased, and the epidemiology of diseases has undergone major changes. In this sequence, there is an increasing incidence of Non-Alcoholic Hepatic Steatosis. This disease ranges from simple steatosis (with a mostly benign course) to non-alcoholic steatohepatitis, which in turn can progress to cirrhosis. Thus, it is of medical interest to detect the presence of non-alcoholic steatohepatitis early in order to prevent further complications. Liver biopsy is the gold standard for histological characterization. However, being an invasive means and associated with several complications, there is a need to consider the use of other complementary means of diagnosis, especially: hepatic ultrasound, computed tomography without contrast, transient hepatic elastrography, acoustic radiation force impulse, magnetic resonance spectroscopy, magnetic resonance elastrography. This review intends to analyze and compare the diagnostic means previously mentioned, paying special attention to the role of transient hepatic elastography in the evaluation of non-alcoholic liver steatosis, since it is a relatively recent and promising technique.
In the world today, the prevalence of obesity has increased, and the epidemiology of diseases has undergone major changes. In this sequence, there is an increasing incidence of Non-Alcoholic Hepatic Steatosis. This disease ranges from simple steatosis (with a mostly benign course) to non-alcoholic steatohepatitis, which in turn can progress to cirrhosis. Thus, it is of medical interest to detect the presence of non-alcoholic steatohepatitis early in order to prevent further complications. Liver biopsy is the gold standard for histological characterization. However, being an invasive means and associated with several complications, there is a need to consider the use of other complementary means of diagnosis, especially: hepatic ultrasound, computed tomography without contrast, transient hepatic elastrography, acoustic radiation force impulse, magnetic resonance spectroscopy, magnetic resonance elastrography. This review intends to analyze and compare the diagnostic means previously mentioned, paying special attention to the role of transient hepatic elastography in the evaluation of non-alcoholic liver steatosis, since it is a relatively recent and promising technique.
Description
Keywords
Elastografia Hepática Transitória Esteato-Hepatite Não-Alcoólica Esteatose Hepática Não-Alcoólica Fibroscan