| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 3.7 MB | Adobe PDF |
Authors
Abstract(s)
O presente relatório é constituído por dois capítulos, sendo o primeiro relativo à componente de investigação e o segundo à experiência profissionalizante em Farmácia Comunitária integradas no plano de estudos do Mestrado Integrado em Ciências Farmacêuticas.
A vertente de investigação incide sobre a temática “Canabinóides sintéticos – Novos fármacos ou drogas de abuso?”.
A canábis é usada há séculos pelos seus benefícios terapêuticos e pelos seus efeitos psicoativos. Na última década, o mesmo tem vindo a acontecer com os canabinóides sintéticos., que foram originalmente desenvolvidos para ajudar a compreender o funcionamento do sistema endocanabinóide. No entanto, o seu potencial terapêutico foi rapidamente reconhecido, abrangendo áreas como a dor, inflamação, emese, desordens do SNC, respiratórias e cardiovasculares, doenças do TGI e musculoesqueléticas, problemas oculares e cancro. Paralelamente apareceram no mercado misturas de plantas e canabinóides sintéticos sob o nome “Spice”, comercializadas como alternativas legais à canábis. A composição destas novas drogas de abuso está constantemente a ser alterada, tornando difícil a sua monitorização e controlo por parte de toxicologistas e legisladores, e pondo em causa o uso de canabinóides sintéticos enquanto terapias inovadoras.
A experiência profissionalizante em Farmácia Comunitária deu-se através da realização de um estágio na Farmácia Oliveira, com a duração de 800 horas. As atividades aqui descritas dão a conhecer a realidade da prática profissional do farmacêutico comunitário, expondo os conhecimentos que adquiri durante a sua realização.
This report is comprised by two chapters, concerning the research component and the professionalizing experience in a Community Pharmacy integrated in the study plan of the Integrated Masters in Pharmaceutical Sciences. The research component focuses on the topic “Synthetic cannabinoids – new medicines or substances of abuse?” Cannabis has been used for centuries because of its therapeutic benefits and its psychoactive effects. In the last decade, the same has been happening with synthetic cannabinoids, which were originally developed to understand the mechanisms involved in the endocannabinoid system. However, their therapeutic potential was soon recognized, in several areas such as pain, inflammation, emesis, central nervous system, respiratory and cardiovascular disorders, eye problems, diseases of the gastrointestinal tract, musculoskeletal disorders and cancer. At the same time, herbal blends mixed with synthetic cannabinoids appeared in the market under the brand name “Spice”, and have been marketed as legal alternatives to cannabis. The composition of these drugs is constantly being changed, making it difficult for toxicologists and legislators to monitor and control these substances, impairing the use of synthetic cannabinoids as novel therapeutic agents. The professionalizing experience in a community pharmacy was carried out in an internship in the Oliveira Pharmacy, lasting 800 hours. The activities here described convey the reality of the professional practice of the community pharmacist, showing the knowledge gathered during this time.
This report is comprised by two chapters, concerning the research component and the professionalizing experience in a Community Pharmacy integrated in the study plan of the Integrated Masters in Pharmaceutical Sciences. The research component focuses on the topic “Synthetic cannabinoids – new medicines or substances of abuse?” Cannabis has been used for centuries because of its therapeutic benefits and its psychoactive effects. In the last decade, the same has been happening with synthetic cannabinoids, which were originally developed to understand the mechanisms involved in the endocannabinoid system. However, their therapeutic potential was soon recognized, in several areas such as pain, inflammation, emesis, central nervous system, respiratory and cardiovascular disorders, eye problems, diseases of the gastrointestinal tract, musculoskeletal disorders and cancer. At the same time, herbal blends mixed with synthetic cannabinoids appeared in the market under the brand name “Spice”, and have been marketed as legal alternatives to cannabis. The composition of these drugs is constantly being changed, making it difficult for toxicologists and legislators to monitor and control these substances, impairing the use of synthetic cannabinoids as novel therapeutic agents. The professionalizing experience in a community pharmacy was carried out in an internship in the Oliveira Pharmacy, lasting 800 hours. The activities here described convey the reality of the professional practice of the community pharmacist, showing the knowledge gathered during this time.
Description
Keywords
Canabinóides Sintéticos Canábis Designer Drugs Farmácia Comunitária Sistema Endocanabinóide Spice