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Introdução: Perante a pandemia da COVID-19 que enfrentamos nos dias de hoje,
torna-se premente a necessidade de evidência científica acerca do seu impacto na
população. Existe um número crescente de casos infetados na população jovem,
incluindo mulheres em idade fértil e grávidas. Estas últimas constituem um grupo de
risco para a infeção por SARS-CoV-2 devido às alterações fisiológicas que ocorrem
durante a gestação, levantando uma preocupação sobre as possíveis complicações
clínicas tanto na mãe como no feto. Neste sentido, esta revisão descritiva pretende
sumarizar a repercussão da COVID-19 nas mulheres grávidas.
Objetivos: revisão descritiva acerca da repercussão da COVID-19 na gravidez.
Metodologia: pesquisa bibliográfica na plataforma Pubmed, de revisões sistemáticas,
escritas em inglês e com texto disponível, até 31 de Janeiro de 2021.
Resultados e Discussção: A gravidez não parece ser um fator de risco para a infeção por
SARS-CoV-2. As grávidas tendem a apresentar um quadro clínico mais brando,
comparativamente à população geral, sendo que a maioria é assintomática e apresenta
menos sintomas de febre, tosse e dispneia. O risco de transmissão vertical é possível,
tendo sido demonstrada a transmissão placentária de SARS-CoV-2, no entanto, este
evento é raro e os recém-nascidos, quando infectados, encontram-se, habitualmente,
assintomáticos ou com doença ligeira. O risco das grávidas infectadas com COVID-19
desenvolverem diabetes gestacional e doença hipetensiva da gravidez não parece ser
superior ao das grávidas que não contraíram COVID-19. O parto prematuro e a
cesariana foram mais frequentes em grávidas infectadas com COVID-19, contudo, as
taxas de mortalidade materna e perinatal revelaram-se semelhantes às da população
geral. A amamentação e o contacto entre a mãe e o recém-nascido são recomendados
somente se aplicadas as medidas de proteção individual. Até ao momento, não existe
um tratamento oficial para a COVID-19 na gravidez.
Conclusão: A infeção por COVID-19 parece não afectar significativamente o desfecho
obstétrico, no entanto, há que vigiar atentamente estas grávidas, enquanto se aguarda a
publicação de mais estudos sobre o assunto.
Introduction: In the view of the COVID-19 pandemic that we face today, there is an urgent need for scientific evidence about its impact on the population. There is an increasing number of infected cases in the young population, including women of childbearing age and pregnant women. The latter constitute a risk group for SARSCoV-2 infection due to the physiological changes that occur during pregnancy, raising concerns about possible clinical complications in both mother and fetus. In this sense, this descriptive review aims to summarize the impact of COVID-19 on pregnant women. Objectives: descriptive review about the impact of COVID-19 on pregnancy. Methodology: bibliographic research on Pubmed platform, only of systematc reviews, written in English and with available text, until January 31th, 2021. Results and Conclusions: Pregnancy does not appear to be a risk factor for SARS-CoV-2 infection. Pregnant women tend to have a milder clinical course of disease, compared to the general population, with more asymptomatic cases and fewer symptoms of fever, cough and dyspnoea. The risk of vertical transmission is possible and placental transmission of SARS-CoV-2 has already been demonstrated, however, this is a rare event and newborns, when infected, are usually asymptomatic or present with mild disease. The risk of pregnant woman infected with COVID-19 developing gestational diabetes and hypertensive pregnancy disease does not appear to be higher than that of pregnant women without COVID-19 infection. Premature birth and cesarean section were more frequent in pregnant women infected with COVID-19, nevertheless, maternal and perinatal mortality rates proved to be similar to those of the general population. Breastfeeding and contact between mother and child are recommended only if individual protection measures are applied. So far, there is no official treatment for COVID-19 in pregnancy. Conclusion: The COVID-19 infection does not seem to affect the obstetric outcomes, however, it is necessary to monitor these pregnant women closely, pending the publication of more studies on the subject.
Introduction: In the view of the COVID-19 pandemic that we face today, there is an urgent need for scientific evidence about its impact on the population. There is an increasing number of infected cases in the young population, including women of childbearing age and pregnant women. The latter constitute a risk group for SARSCoV-2 infection due to the physiological changes that occur during pregnancy, raising concerns about possible clinical complications in both mother and fetus. In this sense, this descriptive review aims to summarize the impact of COVID-19 on pregnant women. Objectives: descriptive review about the impact of COVID-19 on pregnancy. Methodology: bibliographic research on Pubmed platform, only of systematc reviews, written in English and with available text, until January 31th, 2021. Results and Conclusions: Pregnancy does not appear to be a risk factor for SARS-CoV-2 infection. Pregnant women tend to have a milder clinical course of disease, compared to the general population, with more asymptomatic cases and fewer symptoms of fever, cough and dyspnoea. The risk of vertical transmission is possible and placental transmission of SARS-CoV-2 has already been demonstrated, however, this is a rare event and newborns, when infected, are usually asymptomatic or present with mild disease. The risk of pregnant woman infected with COVID-19 developing gestational diabetes and hypertensive pregnancy disease does not appear to be higher than that of pregnant women without COVID-19 infection. Premature birth and cesarean section were more frequent in pregnant women infected with COVID-19, nevertheless, maternal and perinatal mortality rates proved to be similar to those of the general population. Breastfeeding and contact between mother and child are recommended only if individual protection measures are applied. So far, there is no official treatment for COVID-19 in pregnancy. Conclusion: The COVID-19 infection does not seem to affect the obstetric outcomes, however, it is necessary to monitor these pregnant women closely, pending the publication of more studies on the subject.
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Keywords
Covid-19 Maternaloutcomes Neonataloutcomes Pregnancy Sars-Cov2