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Abstract(s)
O presente relatório foi realizado no âmbito da cadeira “Estágio” integrante no Mestrado
Integrado em Ciências Farmacêuticas da Universidade da Beira Interior possuindo dois capítulos.
No capítulo um apresenta-se o trabalho de investigação, desenvolvido no Centro de Investigação
de Ciências da Saúde na Universidade da Beira Interior intitulado “Otimização da Fase Oleosa
de nanoemulsões de fenitoína”. Neste projeto foi aplicado o planeamento estatístico de
experiências para estabelecer qual a melhor formulação anidra para dissolução do fármaco
fenitoína e posterior obtenção da emulsão correspondente. Foram testadas diversas emulsões
sendo avaliadas quanto às suas características de formação, tamanho hidrodinâmico,
osmolalidade, transmitância e viscosidade, avaliando-se qual a emulsão que apresentava, no
seu conjunto, as melhores características.
No capítulo dois apresenta-se descrito o período de estágio em farmácia comunitária, realizado
na Farmácia Ferreira Leite em Fafe (Braga, Portugal) por um período de 800 horas. Onde se
apresentam as atividades realizadas, bem como todo o circuito do medicamento dentro de uma
farmácia comunitária.
This report was written as part of the subject “Estágio” of the Pharmaceutical Sciences Masters Degree of University of Beira Interior having two chapters. Chapter one presents the research work, developed at the Health Sciences Research Centre of University of Beira Interior entitled “Optimization of the oily phase in Phenytoin Nanoemulsions”. In this project was used the design of experiments to establish the best anhydrous formulation to promote the phenytoin dissolution and posteriorly elaboration of the correspondent emulsion. Several emulsions were tested in relation to their formation characteristics, hydrodynamic size, osmolality, transmittance and viscosity, evaluating which emulsion presented, as a whole, the best characteristics. The chapter two describes the period of internship in community pharmacy, held at the Farmácia Ferreira Leite in Fafe (Braga, Portugal) for a period of 800 hours. Where the activities performed within community pharmacy, as well as the whole circuit of the drug, are presented.
This report was written as part of the subject “Estágio” of the Pharmaceutical Sciences Masters Degree of University of Beira Interior having two chapters. Chapter one presents the research work, developed at the Health Sciences Research Centre of University of Beira Interior entitled “Optimization of the oily phase in Phenytoin Nanoemulsions”. In this project was used the design of experiments to establish the best anhydrous formulation to promote the phenytoin dissolution and posteriorly elaboration of the correspondent emulsion. Several emulsions were tested in relation to their formation characteristics, hydrodynamic size, osmolality, transmittance and viscosity, evaluating which emulsion presented, as a whole, the best characteristics. The chapter two describes the period of internship in community pharmacy, held at the Farmácia Ferreira Leite in Fafe (Braga, Portugal) for a period of 800 hours. Where the activities performed within community pharmacy, as well as the whole circuit of the drug, are presented.
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Keywords
Farmácia Comunitária Fenitoína Nanoemulsões Planeamento Estatístico de Experiências