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Abstract(s)
Introdução: A nível mundial, a Chlamydia trachomatis (CT) e Neisseria gonorrhoeae
(NG) causam por ano cerca de 129 milhões e 82 milhões de novas infeções, respetivamente.
A incapacidade de diagnosticar e tratar estas infeções atempadamente, sobretudo por serem
frequentemente assintomáticas, pode conduzir a complicações e sequelas importantes.
Atualmente, ainda não existem em Portugal dados nacionais fidedignos da prevalência
destas infeções.
Objetivos: Como objetivo principal deste trabalho pretendeu-se avaliar a prevalência das
infeções por C. trachomatis e N. gonorrhoeae no laboratório do Centro Hospitalar
Universitário Cova da Beira no período de agosto de 2012 a dezembro de 2021, tendo como
última finalidade fundamentar a eventual necessidade de elaboração de programas de
rastreio e outras medidas de controlo destas infeções.
Materiais e Métodos: Este é um estudo observacional, analítico e retrospetivo
concretizado com recurso aos processos clínicos dos utentes testados para CT e/ou NG por
PCR no laboratório do CHUCB no período de 2012 a 2021. Foram incluídos 692 utentes
após aplicação de critérios de inclusão e exclusão.
Resultados: No presente estudo obteve-se uma prevalência de infeção por CT de 3,9%
(n=27) e por NG de 2,8% (n=17). As faixas etárias dos 0-14, dos 15-19 e 20-24 anos foram
as que registaram maior prevalência de infeção por CT (16,7%, 15,8% e 10,8%,
respetivamente). A infeção por NG foi mais prevalente nas faixas etárias dos 15-19 (15,8%)
e 20-24 anos (6,8%). O sexo masculino foi o que apresentou maior prevalência de ambas
as infeções: 4,8% para a CT e 5.8% para a NG. Foi possível evidenciar uma correlação
estatisticamente significativa (considerando uma significância de 5%) entre as faixas etárias
mais jovens e a maior prevalência de infeção por CT (? = 0,000) e por NG (? = 0,021).
Verificou-se ainda uma maior prevalência de infeção para NG no sexo masculino (? =
0,000), assim como uma maior prevalência de infeção para CT no grupo testado em outras
consultas (?= 0,043), ambas com relevância estatística.
Conclusão: Apesar de os resultados obtidos neste estudo não puderem ser transpostos
para a globalidade da população portuguesa, alertam-nos para alguns grupos (população
jovem e do sexo masculino) que possam ser mais vulneráveis a este tipo de infeções. Poderá,
assim, haver vantagem em implementar programas de rastreio mais direcionados à população mais suscetível, de modo a poderem ser diminuídas as comorbilidades
resultantes destas infeções.
Introduction: Worldwide, Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) cause about 129 million and 82 million new infections per year, respectively. The inability to diagnose and treat these infections in a timely manner, mainly because they are often asymptomatic, can lead to important complications and sequelae. Currently, there are still no reliable national data on the prevalence of these infections in Portugal. Objectives: The main objective of this work was to evaluate the prevalence of infections by C. trachomatis and N. gonorrhoeae in the laboratory of Centro Hospitalar Universitário Cova da Beira from August 2012 to December 2021, with the ultimate purpose of substantiating the eventual need to develop screening programs and other measures to control these infections. Materials and Methods: This is an observational, analytical and retrospective study carried out using the clinical files of users tested for CT and/or NG by PCR in the CHUCB laboratory from 2012 to 2021. 692 users were included after applying inclusion and exclusion criteria. Results: In the present study, there was a prevalence of infection by CT of 3.9% (n=27) and by NG of 2.8% (n=17). The age groups 0-14, 15-19 and 20-24 years were the ones that recorded the highest prevalence of CT infection (16.7%, 15.8% and 10.8%, respectively). NG infection was more prevalent in the 15-19 (15.8%) and 20-24 (6.8%) age groups. Males showed the highest prevalence of both infections: 4.8% for CT and 5.8% for NG. It was possible to show a statistically significant correlation between the younger age groups and the higher prevalence of CT (? = 0.000) and NG (? = 0.021) infection. There was also a higher prevalence of infection for NG in males (? = 0.000), as well as a higher prevalence of infection for CT in the group tested in other consultations (? = 0.043), both with statistical significance. Conclusion: Although the results obtained in this study cannot be transposed to the portuguese population as a whole, they alert us to the fact that some groups (young and male population) may be more vulnerable to this type of infections. There may therefore be an advantage in implementing screening programs that are more targeted at the most susceptible population so that the comorbidities resulting from these infections can be reduced.
Introduction: Worldwide, Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) cause about 129 million and 82 million new infections per year, respectively. The inability to diagnose and treat these infections in a timely manner, mainly because they are often asymptomatic, can lead to important complications and sequelae. Currently, there are still no reliable national data on the prevalence of these infections in Portugal. Objectives: The main objective of this work was to evaluate the prevalence of infections by C. trachomatis and N. gonorrhoeae in the laboratory of Centro Hospitalar Universitário Cova da Beira from August 2012 to December 2021, with the ultimate purpose of substantiating the eventual need to develop screening programs and other measures to control these infections. Materials and Methods: This is an observational, analytical and retrospective study carried out using the clinical files of users tested for CT and/or NG by PCR in the CHUCB laboratory from 2012 to 2021. 692 users were included after applying inclusion and exclusion criteria. Results: In the present study, there was a prevalence of infection by CT of 3.9% (n=27) and by NG of 2.8% (n=17). The age groups 0-14, 15-19 and 20-24 years were the ones that recorded the highest prevalence of CT infection (16.7%, 15.8% and 10.8%, respectively). NG infection was more prevalent in the 15-19 (15.8%) and 20-24 (6.8%) age groups. Males showed the highest prevalence of both infections: 4.8% for CT and 5.8% for NG. It was possible to show a statistically significant correlation between the younger age groups and the higher prevalence of CT (? = 0.000) and NG (? = 0.021) infection. There was also a higher prevalence of infection for NG in males (? = 0.000), as well as a higher prevalence of infection for CT in the group tested in other consultations (? = 0.043), both with statistical significance. Conclusion: Although the results obtained in this study cannot be transposed to the portuguese population as a whole, they alert us to the fact that some groups (young and male population) may be more vulnerable to this type of infections. There may therefore be an advantage in implementing screening programs that are more targeted at the most susceptible population so that the comorbidities resulting from these infections can be reduced.
Description
Keywords
Chlamydia Trachomatis Neisseria Gonorrhoeae Rastreio