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Abstract(s)
IntroduĆ§Ć£o: A trombose dos seios venosos Ć© uma patologia que cursa com uma
apresentaĆ§Ć£o clĆnica que dificulta o seu diagnĆ³stico. A terapĆŖutica nestes casos consiste,
frequentemente, em anticoagulaĆ§Ć£o e o seu principal objetivo Ć© recanalizar os vasos
afetados, traduzindo-se num melhor outcome para o doente. Assim, o objetivo deste
estudo Ć© identificar eventuais fatores que influenciem no prognĆ³stico da recanalizaĆ§Ć£o
nestes episĆ³dios.
MĆ©todos: Trata-se de um estudo observacional e retrospetivo que inclui todos os
doentes diagnosticados com trombose dos seios venosos no Hospital de Braga, num
perĆodo de cinco anos, com a exclusĆ£o de doentes com etiologia infeciosa ou
traumĆ”tica. Estudaram-se as suas caracterĆsticas sociodemogrĆ”ficas, antecedentes
pessoais, apresentaĆ§Ć£o clĆnica, caracterizaĆ§Ć£o imagiolĆ³gica e avaliaĆ§Ć£o pĆ³s-evento. A
anƔlise descritiva de dados foi realizada com recurso aos testes t, Mann-Whitney U,
qui-quadrado ou Teste de Fisher. Admitiu-se significĆ¢ncia estatĆstica se p<0.05.
Resultados: Identificou-se uma associaĆ§Ć£o estatisticamente significativa entre o tipo
de recanalizaĆ§Ć£o e a avaliaĆ§Ć£o funcional aos seis meses (Teste de Fisher, p = 0.022, Fc
= 0.38). Verificaram-se associaƧƵes estatisticamente significativas entre a recanalizaĆ§Ć£o
e a idade (t (41) = -3.80, p < 0.001, d = 1.81), e com a existĆŖncia de dĆ©fice neurolĆ³gico Ć
apresentaĆ§Ć£o clĆnica (Teste de Fisher, p = 0.021, F = -0.38). Observa-se que a maioria
dos doentes que nĆ£o recanalizou apresentava uma idade superior, comparativamente
aos restantes, e dĆ©fice neurolĆ³gico Ć manifestaĆ§Ć£o do episĆ³dio.
ConclusĆ£o: Os dados obtidos pertencem a uma amostra pequena, o que limita a
objetivaĆ§Ć£o da influĆŖncia da recanalizaĆ§Ć£o no prognĆ³stico do doente, sendo necessĆ”rio
estabelecer estas relaƧƵes em estudos subsequentes. No entanto, este estudo permite
uma reflexĆ£o importante sobre fatores trombĆ³ticos.
Introduction: Cerebral venous thrombosis is a difficult diagnosis pathology due to its several clinical presentations. Anticoagulation is the standard treatment regarding the recanalization of the affected blood vessels resulting and as a in patientās better outcome. This work intends to identify factors that may influence the prognosis of the recanalization in these episodes. Methods: This is an observational and retrospective study that includes all patients diagnosed with CVT in Hospital de Braga, in a 5 year period. Infectious or traumatic cerebral venous thrombosis were excluded. Sample sociodemographic characteristics, medical registry, clinical presentation, imagiologic characterization and evaluation post event were analysed. A descriptive analysis was conducted and t test, Mann-Whitney U test, chi-square test and Fisher exact test were used. Statistical significance was recognized at p<0.05. Results: A statistically significant association was established between the type of recanalization and the functional evaluation at 6 months (Fisherās test, p=0.022, Fc = 0.38). Statistically significant association was also found between recanalization and the age (t(41) = -3.80, p < 0.001, d = 1.81), and the presence of a neurological deficit in clinical presentation (Fisherās test, p = 0.021, F = -0.38). It is possible to observe that patients with no recanalization had an older age and a neurological deficit at clinical presentation comparing the rest of the sample. Conclusion: This data refers to a small sample which conditioned a reliable evaluation of the influence of recanalization in patient's prognosis. These types of associations request more studies to be established. Nevertheless, this study allowed a major reflection on prothrombotic factors.
Introduction: Cerebral venous thrombosis is a difficult diagnosis pathology due to its several clinical presentations. Anticoagulation is the standard treatment regarding the recanalization of the affected blood vessels resulting and as a in patientās better outcome. This work intends to identify factors that may influence the prognosis of the recanalization in these episodes. Methods: This is an observational and retrospective study that includes all patients diagnosed with CVT in Hospital de Braga, in a 5 year period. Infectious or traumatic cerebral venous thrombosis were excluded. Sample sociodemographic characteristics, medical registry, clinical presentation, imagiologic characterization and evaluation post event were analysed. A descriptive analysis was conducted and t test, Mann-Whitney U test, chi-square test and Fisher exact test were used. Statistical significance was recognized at p<0.05. Results: A statistically significant association was established between the type of recanalization and the functional evaluation at 6 months (Fisherās test, p=0.022, Fc = 0.38). Statistically significant association was also found between recanalization and the age (t(41) = -3.80, p < 0.001, d = 1.81), and the presence of a neurological deficit in clinical presentation (Fisherās test, p = 0.021, F = -0.38). It is possible to observe that patients with no recanalization had an older age and a neurological deficit at clinical presentation comparing the rest of the sample. Conclusion: This data refers to a small sample which conditioned a reliable evaluation of the influence of recanalization in patient's prognosis. These types of associations request more studies to be established. Nevertheless, this study allowed a major reflection on prothrombotic factors.
Description
Keywords
AnticoagulaĆ§Ć£o PrognĆ³stico RecanalizaĆ§Ć£o Seios Venosos Trombose