Publication
Prevalence and clinical features of adverse food reactions in Portuguese adolescents
dc.contributor.author | Lozoya-Ibáñez, Carlos | |
dc.contributor.author | Morgado-Nunes, Sara | |
dc.contributor.author | Rodrigues, Alexandra | |
dc.contributor.author | Fernandes, Patrícia | |
dc.contributor.author | Lourenço, Olga | |
dc.contributor.author | Fonseca, Ana Mafalda | |
dc.contributor.author | Barata, Luís Taborda | |
dc.date.accessioned | 2021-07-05T10:45:43Z | |
dc.date.available | 2021-07-05T10:45:43Z | |
dc.date.issued | 2020-08 | |
dc.description.abstract | Background & aims: The objective of the present study was to determine, for the first time, the prevalence and clinical features of food allergy in Portuguese adolescents. Methods: Cross-sectional study performed in various secondary schools in central Portugal. Randomly selected adolescents replied to a validated food allergy questionnaire. Those who reported an adverse food reaction were seen at participating hospitals, where clinical history was taken, skin prick (SPT) and prick-prick skin (SPPT) tests were performed, and food allergen-specific IgE levels (sIgE) were determined. An open oral challenge was performed in selected cases. Cases of positive clinical history of immediate (up to 2 h after ingestion) reaction in association with positive food sIgE levels and/or SPT were classified as IgE-associated probable food allergy and as confirmed IgE-mediated food allergy if food challenges were positive. Cases of positive clinical history of delayed (more than 2 h after ingestion) and negative food sIgE levels independently of positive SPT or SPPT results, were classified as non-IgE associated probable food allergy. Results: The prevalence of probable food allergy in Portuguese adolescents was 1.41% (95% CI: 0.90–2.03%), with fresh fruits, shellfish, nuts, and peanut as the most frequently implicated foods. IgE-mediated probable food allergy occurred in 1.23% (95% CI: 0.67–1.72%) of cases, with fresh fruits, shellfish, and nuts mainly involved. Cutaneous symptoms were most frequently reported. Conclusions: The prevalence of probable food allergies in Portuguese adolescents is low, is mostly related to fresh fruits, shellfish, nuts, and peanut, and most frequently involves cutaneous symptoms. | pt_PT |
dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
dc.identifier.doi | 10.1016/j.waojou.2020.100453 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10400.6/11186 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
dc.subject | Adolescents | pt_PT |
dc.subject | Adverse food reaction | pt_PT |
dc.subject | Food allergy | pt_PT |
dc.subject | Prevalence | pt_PT |
dc.subject | Cutaneous tests | pt_PT |
dc.subject | Open food challenge | pt_PT |
dc.title | Prevalence and clinical features of adverse food reactions in Portuguese adolescents | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.citation.issue | 8 | pt_PT |
oaire.citation.startPage | 100453 | pt_PT |
oaire.citation.title | The World Allergy Organization Journal | pt_PT |
oaire.citation.volume | 13 | pt_PT |
person.familyName | Lourenço | |
person.familyName | Loureiro Fonseca | |
person.familyName | Taborda Barata | |
person.givenName | Olga Maria Marques | |
person.givenName | Ana Mafalda | |
person.givenName | Luis | |
person.identifier | H-3836-2012 | |
person.identifier | 104007 | |
person.identifier.ciencia-id | 6618-1C4C-D1B7 | |
person.identifier.ciencia-id | A61D-657A-6DD0 | |
person.identifier.ciencia-id | 1E1F-8A43-055B | |
person.identifier.orcid | 0000-0002-8401-5976 | |
person.identifier.orcid | 0000-0003-1118-5525 | |
person.identifier.orcid | 0000-0001-6649-8890 | |
person.identifier.scopus-author-id | 15128160500 | |
rcaap.rights | openAccess | pt_PT |
rcaap.type | article | pt_PT |
relation.isAuthorOfPublication | c890c74a-abc1-4910-aa70-f0da7b4ad902 | |
relation.isAuthorOfPublication | 34cfbd2d-5537-4aba-8552-3e2e4d48b473 | |
relation.isAuthorOfPublication | 3f1ad371-56e3-4fda-9409-748e355a0de1 | |
relation.isAuthorOfPublication.latestForDiscovery | 34cfbd2d-5537-4aba-8552-3e2e4d48b473 |
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