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Abstract(s)
A osteoporose carateriza-se por tratar – se de uma patologia sistêmica do esqueleto que causa
um desequilíbrio da remodelação óssea. Esta apresenta uma etiologia poligenética
influenciada por fatores ambientais que causa fraturas de fragilidade, essencialmente a nível
vertebral, anca e rádio. Com maior longevidade e qualidade de vida é necessário um manejo
racional da osteoporose e a necessidade de atualização para com os diversos tratamentos e
acesso a pesquisas visando minimizar consequências secundárias. Um apelo a ação. Os
métodos de diagnóstico existentes atualmente englobam a utilização de marcadores de
remodelação óssea, mas não permitem avaliar outras propriedades do esqueleto, como a
qualidade do tecido ósseo e a sua resistência. O método mais utilizado é a absorciometria
radiológica de dupla energia, que permite determinar a densidade mineral óssea.
Clinicamente a osteoporose manifesta-se pela ocorrência de fraturas. Por norma o seu
tratamento engloba agentes farmacológicos, mas podem ser aplicadas alterações de estilos de
vida que atenuam a sintomatologia, como a atividade física e nutrição, englobando o correto
aporte de cálcio e vitamina D.
Osteoporosis is a systemic skeletal disorder which results from an imbalance in bone remodeling. It’s a polygenetic, environmentally modifiable disease, which precipitates into fragility fractures of vertebrae, hip and radius. Although the idea of “bone quality” is conceptually useful, except for bone turnover markers, methods are not currently available for the clinical assessment of other properties of bone that determine bone strength. Thus, for now and the near future, measurement of bone density, testing with dual-energy x-ray absorptiometry (DEXA), remains the primary technique for the diagnosis of osteoporosis and for monitoring treatment. Osteoporosis only causes symptoms or impact on the patient when there is a fracture. Low bone density is one of the main risk factors for fracture, but not the only one. Although osteoporosis treatment typically involves the use of pharmacologic agents, it is well-known that lifestyle interventions such as physical activity and adequate nutrition both play a key role in bone health, including calcium and vitamin D.
Osteoporosis is a systemic skeletal disorder which results from an imbalance in bone remodeling. It’s a polygenetic, environmentally modifiable disease, which precipitates into fragility fractures of vertebrae, hip and radius. Although the idea of “bone quality” is conceptually useful, except for bone turnover markers, methods are not currently available for the clinical assessment of other properties of bone that determine bone strength. Thus, for now and the near future, measurement of bone density, testing with dual-energy x-ray absorptiometry (DEXA), remains the primary technique for the diagnosis of osteoporosis and for monitoring treatment. Osteoporosis only causes symptoms or impact on the patient when there is a fracture. Low bone density is one of the main risk factors for fracture, but not the only one. Although osteoporosis treatment typically involves the use of pharmacologic agents, it is well-known that lifestyle interventions such as physical activity and adequate nutrition both play a key role in bone health, including calcium and vitamin D.
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Keywords
Bio Marcadores Causas Secundarias Envelhecimento Osteoporose Prevenção Tratamento.