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Advisor(s)
Abstract(s)
A vitamina D tem como objetivo essencial a regulação de vários processos fisiológicos e
tem sido relacionada com diversas patologias.
A elevada prevalência de vitamina D é, hoje em dia, considerada como um problema de
saúde pública que afeta vários países da Europa e os EUA e ocorre com frequência no
mundo todo.
Não nos podemos esquecer também, que alimentos naturais, raramente fornecem uma
quantidade suficiente de Vitamina D para suprir a sua falta. Por outro lado, alimentos
enriquecidos com vitamina D e suplementos de vitamina D podem ajudar a preveni-la
quando exposição solar for inadequada.
Existem cada vez mais evidências recentes, que correlacionam níveis insuficientes de
vitamina D, com um risco aumentado de desenvolvimento de várias doenças, não apenas
relacionadas com a componente óssea.
Nos últimos anos, o papel fisiológico da vitamina D tem sido largamente estudado e
graças a isso a sua ação no metabolismo do cálcio é já bem conhecida, sendo esta uma
das hormonas responsáveis pela manutenção dos níveis de cálcio sérico, através da
promoção da absorção de cálcio e fósforo a partir do intestino e da reabsorção óssea de
cálcio.
Contudo a importância clínica na vitamina D não acaba ou se esgota no metabolismo
fosfocálcio, pois esta manifesta-se igualmente em várias outras condições médicas, como
por exemplo diabetes, doenças cardiovasculares, esclerose múltipla, cancro, distúrbios
psiquiátricos, doenças neuromusculares.
Partindo deste princípio, e tendo consciência do crescente número de doenças associadas
a esta deficiência, nos últimos anos, tem-se verificado um aumento significativo do
interesse pela vitamina D, tornando-se num tópico mediático, muito discutido pelos
profissionais de saúde e pelos cidadãos em geral, dada a elevada relevância na clínica,
que nos propomos explorar ao longo desta dissertação Questões como a importância fisiológica da vitamina D, complicações associadas ao seu
défice, necessidade de rastreio dos níveis normais, e sua suplementação, vêm sendo
amplamente debatidos.
Vitamin D has as its essential objective the regulation of several physiological processes and has been related to several pathologies. The high prevalence of vitamin D is nowadays considered a public health problem that affects several countries in Europe and the USA and occurs frequently throughout the world. We can't forget, too, that natural foods rarely provide a sufficient amount of Vitamin D to make up for the lack. On the other hand, foods enriched with vitamin D and vitamin D supplements can help prevent it when sun exposure is inadequate. There is increasing recent evidence that correlates insufficient levels of vitamin D with an increased risk of developing several diseases, not only related to the bone component. In recent years, the physiological role of vitamin D has been widely studied and, thanks to this, its action on calcium metabolism is already well known, being one of the hormones responsible for maintaining serum calcium levels, through the promotion of calcium absorption. calcium and phosphorus from the intestine and bone resorption of calcium. However, the clinical importance of vitamin D does not end or is exhausted in the phosphocalcium metabolism, as this is also manifested in several other medical conditions, such as diabetes, cardiovascular diseases, multiple sclerosis, cancer, psychiatric disorders, neuromuscular diseases. Based on this principle, and being aware of the growing number of diseases associated with this deficiency, in recent years there has been a significant increase in interest in vitamin D, becoming a media topic, much discussed by health professionals and citizens. in general, given the high relevance in the clinic, which we propose to explore throughout this dissertation. Issues such as the physiological importance of vitamin D, complications associated with its deficiency, the need for screening for normal levels, and its supplementation, have been widely debated.
Vitamin D has as its essential objective the regulation of several physiological processes and has been related to several pathologies. The high prevalence of vitamin D is nowadays considered a public health problem that affects several countries in Europe and the USA and occurs frequently throughout the world. We can't forget, too, that natural foods rarely provide a sufficient amount of Vitamin D to make up for the lack. On the other hand, foods enriched with vitamin D and vitamin D supplements can help prevent it when sun exposure is inadequate. There is increasing recent evidence that correlates insufficient levels of vitamin D with an increased risk of developing several diseases, not only related to the bone component. In recent years, the physiological role of vitamin D has been widely studied and, thanks to this, its action on calcium metabolism is already well known, being one of the hormones responsible for maintaining serum calcium levels, through the promotion of calcium absorption. calcium and phosphorus from the intestine and bone resorption of calcium. However, the clinical importance of vitamin D does not end or is exhausted in the phosphocalcium metabolism, as this is also manifested in several other medical conditions, such as diabetes, cardiovascular diseases, multiple sclerosis, cancer, psychiatric disorders, neuromuscular diseases. Based on this principle, and being aware of the growing number of diseases associated with this deficiency, in recent years there has been a significant increase in interest in vitamin D, becoming a media topic, much discussed by health professionals and citizens. in general, given the high relevance in the clinic, which we propose to explore throughout this dissertation. Issues such as the physiological importance of vitamin D, complications associated with its deficiency, the need for screening for normal levels, and its supplementation, have been widely debated.
Description
Keywords
Doenças Associadas à Vitamina D Fontes de Vitamina D Níveis Séricos de Vitamina D Vitamina D