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Advisor(s)
Abstract(s)
A presente dissertação encontra-se inserida na unidade curricular “Estágio Curricular do
Mestrado Integrado de Ciências Farmacêuticas”.
Este trabalho é constituído por 3 partes distintas: a primeira parte referente ao trabalho de
pesquisa bibliográfica, uma revisão da literatura no âmbito da fitoquímica e propriedades
farmacológicas do Género Rubia, assim como a sua potencial aplicação na Medicina
Tradicional; uma segunda parte que aborda o relatório de estágio curricular que realizei em
farmácia hospitalar; e uma terceira parte relativa ao relatório de estágio curricular realizado
em farmácia comunitária.
O primeiro capítulo, intitula-se “O Género Rubia: usos na medicina tradicional, fitoquímica
e propriedades farmacológicas”. Rubia constitui um dos géneros da família Rubiaceae,
encontrando-se distribuído um pouco por todo o Portugal Continental.
Desde sempre que as plantas são utilizadas no tratamento e prevenção de determinadas
patologias, existindo registo do uso de extratos de Rubia. Atualmente, estudos in vitro e in
vivo comprovam um extenso número de propriedades farmacológicas das plantas deste
género, tais como, atividade antioxidante, antimicrobiana, anticancerígena, entre outras.
Os diferentes estudos são unânimes em considerar que tais propriedades se devem
principalmente aos compostos antraquinónicos encontrados nas espécies de Rubia, como,
por exemplo, alizarina e purpurina.
Dada a crescente procura de plantas medicinais no âmbito do tratamento de doenças
crónicas ou no âmbito da resistência antimicrobiana, torna-se fulcral a procura de
alternativas para uso no homem, sem descartar a questão da segurança.
O segundo capítulo é referente ao estágio em farmácia hospitalar, realizado no Hospital
Sousa Martins, na Guarda, num total de 273 horas, enquanto o terceiro capítulo refere-se
ao estágio em farmácia comunitária, na Farmácia Viriato, em Viseu. Nestes capítulos, são
descritas algumas atividades por mim realizadas, bem como o funcionamento dos serviços.
The following dissertation is included in the curricular unit “Curricular Internship of the Integrated Master's Degree in Pharmaceutical Sciences”. This work consists of three distinct parts: the first refers to the bibliographical research work, a review of the literature within the scope of the phytochemistry and pharmacological properties of Rubia Genus, as well as its potential application in traditional medicine; a second part that addresses the report of the curricular internship I carried out in a hospital pharmacy; and a third part relating to the report on the curricular internship carried out in a community pharmacy. The first chapter is entitled “The Rubia Genus: uses in traditional medicine, phytochemistry and pharmacological properties”. Rubia is one of the Rubiaceae family kind, and is distributed throughout Portugal. Since always, plants have been used in the treatment and prevention of certain pathologies, and there are records of the use of Rubia extracts. Currently, in vitro and in vivo studies prove a large number of its pharmacological properties, such as antioxidant, antimicrobial, antitumor activity, among others, presented later. The studies are unanimous in considering that such properties are mainly due to the anthraquinone compounds found in Rubia species, such as alizarin and purpurin. Given the growing demand for medicinal plants in the treatment of chronic diseases or in the context of antimicrobial resistance, the search for alternatives for use in humans becomes crucial, without discarding the issue of safety. The second chapter refers to the internship in the hospital pharmacy, carried out at Hospital Sousa Martins, in Guarda, for a total of 273 hours, while the third chapter refers to the internship in the community pharmacy, at Farmácia Viriato, in Viseu. In these chapters, some activities I carried out are described, as well as how the services work.
The following dissertation is included in the curricular unit “Curricular Internship of the Integrated Master's Degree in Pharmaceutical Sciences”. This work consists of three distinct parts: the first refers to the bibliographical research work, a review of the literature within the scope of the phytochemistry and pharmacological properties of Rubia Genus, as well as its potential application in traditional medicine; a second part that addresses the report of the curricular internship I carried out in a hospital pharmacy; and a third part relating to the report on the curricular internship carried out in a community pharmacy. The first chapter is entitled “The Rubia Genus: uses in traditional medicine, phytochemistry and pharmacological properties”. Rubia is one of the Rubiaceae family kind, and is distributed throughout Portugal. Since always, plants have been used in the treatment and prevention of certain pathologies, and there are records of the use of Rubia extracts. Currently, in vitro and in vivo studies prove a large number of its pharmacological properties, such as antioxidant, antimicrobial, antitumor activity, among others, presented later. The studies are unanimous in considering that such properties are mainly due to the anthraquinone compounds found in Rubia species, such as alizarin and purpurin. Given the growing demand for medicinal plants in the treatment of chronic diseases or in the context of antimicrobial resistance, the search for alternatives for use in humans becomes crucial, without discarding the issue of safety. The second chapter refers to the internship in the hospital pharmacy, carried out at Hospital Sousa Martins, in Guarda, for a total of 273 hours, while the third chapter refers to the internship in the community pharmacy, at Farmácia Viriato, in Viseu. In these chapters, some activities I carried out are described, as well as how the services work.
Description
Keywords
Atividade Farmacológica Farmácia
Comunitária Farmácia Hospitalar Fitoquímica Plantas Medicinais Rubia
Tinctorum Rubia Rubia Cordifolia Rubia Peregrina Toxicidade