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Rodrigues Simões, José Augusto

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  • Coffee Consumption and Blood Pressure: Results of the Second Wave of the Cognition of Older People, Education, Recreational Activities, Nutrition, Comorbidities, and Functional Capacity Studies (COPERNICUS)
    Publication . Kujawska, Agnieszka; Kujawski, Sławomir; Hajec, Weronika; Skierkowska, Natalia; Kwiatkowska, Małgorzata; Husejko, Jakub; Newton, Julia; Simões, José Augusto Rodrigues; Zalewski, Pawel; Kędziora-Kornatowska, Kornelia
    This study examined the relationship between the frequency of coffee consumption and blood pressure over a two year follow up of a cohort of elderly people. Healthy, older people (N = 205) were examined at baseline and at two years. Participants completed physical and behavioural assessments, which included body composition, current pharmacological treatment, and frequency of coffee consumption grouped into three categories: “never to a few times per month”, “once a week to a few times per week”, and “every day”. Blood pressure (systolic (sBP), diastolic (dBP), mean (mBP), and pulse pressure (PP)) was measured at baseline and after two years. After adjusting for body composition, smoking status, age, sex, heart rate, and number of antihypertensive agents taken, participants who drank coffee everyday had a significant increase in sBP, with a mean of 8.63 (1.27; 15.77) and an mBP, with a mean of 5.55 mmHg (0.52; 10.37) after two years (t = 2.37, p = 0.02 and t = 2.17, p = 0.03, respectively) compared to participants who never or very rarely (up to a few times per month) drank coffee. DBP and PP were not affected by coffee consumption frequency in a statistically significant manner.
  • Prevalence of chronic obstructive pulmonary disease in general practice patients in the Central Region of Portugal
    Publication . Ricardo, Jéssica; Simões, José Augusto Rodrigues; Santiago, Luiz Miguel de Mendonça Soares
    Introduction COPD is a common worldwide condition associated with morbidity and mortality. Its symptoms can be easily overlooked, accounting for an elevated level of under-recognition and under-diagnosis. Knowledge of the prevalence of COPD and the significance of its associated factors in the population enables better management of medical resources. To establish the prevalence of COPD in General Practice patients in the Central Region of Portugal and analyze the correlation with associated factors. Material and methods Cross-sectional study of patients’ data with COPD (R95, International Classification for Primary Care 2), anonymously gathered from the official database of the Central Health Administration of Portugal. Results Out of 937,817 individuals, 24,148 patients were identified with COPD, a prevalence of 2.57/100,000. 73.7% were above 65 years of age, and 60.2% were males. BMI was recorded in 60.2% patients, FEV1(%) in 8.0%, and smoking pack-years in 37.1%. Age and BMI were significantly negatively correlated (ρ = -0.032, p < 0.001), with the same occurring between age and FEV1(%) (ρ = -0.073, p < 0.05). A strong association of COPD with male gender and older age groups was found. Conclusions The prevalence of COPD was significantly higher in males, and age was identified as a risk factor for this condition. Higher age was non-significantly associated with lower FEV1(%) and significantly associated with BMI. The lack of e-records calls for an improvement.
  • Pessoas que sofrem de hipertensão arterial: implicações na atividade médica das diferenças entre os controlados e os não controlados
    Publication . Martins, Ricardo; Santiago, Luiz Miguel de Mendonça Soares; Reis, Maria Teresa; Roque, Ana Carolina; Pinto, Mariana; Simões, José Augusto Rodrigues; Rosendo, Inês
    Objetivos: Comparar características clínicas, de atividade médica e de caracterização familiar e social entre populações sofrendo de hipertensão arterial segundo estejam ou não controladas. Metodologia Estudo observacional em amostra aleatória por ordem alfabética e representativa com reposição em população de cuidados de saúde primários de 25 médicos especialistas em medicina geral e familiar de três unidades de cuidados de saúde primários no centro de Portugal, em 2018, pela análise dos registos clínicos informáticos das pessoas com a classificação ICPC‐2 de hipertensão arterial. Estudaram‐se variáveis epidemiológicas, clínicas, familiares, sociais e de atividade médica terapêutica. Realizou‐se estatística descritiva e inferencial. Resultados Num universo de 8750 pessoas com a classificação hipertensão arterial estudou‐se uma amostra de n = 387 (tamanho calculado para IC 95% e margem de erro de 5% em n = 369). Hipertensão arterial não controlada em 56,1% da amostra, significativamente mais frequente em quem vive só (p = 0,024), vive em família nuclear (p = 0,011), em situação de mais baixa classificação social (p = 0,018), com prescrição concomitante de AINE (p = 0,018). O risco cardiovascular calculado é não significativamente mais elevado no não controlo (p = 0,116). A inércia terapêutica não se verifica em número de associações e em número médio de medicamentos (p = 0,274) não se verificando igualmente diferença para as restantes variáveis estudadas. Viver só, pertencer a famílias com mais baixa classificação social e viver em família nuclear representam 9,6% da responsabilidade de não haver controlo. Conclusões A atividade médica no ambiente de medicina geral e familiar, e não só, deve assim aliar as competências terapêuticas com as habilidades de estudo individual e social para a melhoria do controlo da HTA em Portugal.
  • Adherence to Antihypertensive Therapy and Its Determinants: A Systematic Review
    Publication . Ferreira, Pedro Duarte De Sousa; Simões, José Augusto Rodrigues; Velho, Denise Alexandra Cunha
    Hypertension is a globally prevalent condition, and low adherence to antihypertensive therapy is considered one of the main causes of poor blood pressure (BP) control. Non-adherence to antihypertensive treatment is a complex issue that can arise from various factors; however, gaining an understanding of this provides key targets for intervention strategies. This study aimed to provide an overview of the current status and recent developments regarding our understanding of the determinants of patients' adherence to antihypertensives. A systematic review was performed using the electronic databases MEDLINE/PubMed, Web of Science, Scientific Electronic Library Online (SciELO), and “Índex das Revistas Médicas Portuguesas”, which included studies published between 2017 and 2021 following the PICOS model: (P) Adult patients with the diagnosis of primary hypertension, using at least one antihypertensive agent; (I) all interventions on both pharmacological and non-pharmacological level; (C) patient’s adherence against their non-adherence; (O) changes in adherence to the therapeutic plan; and (S) any study design (except review articles) written in English, French, Spanish or Portuguese. Articles were reviewed by two researchers and their quality was assessed. Subsequently, determinants were classified according to their consistent or inconsistent association with adherence or non-adherence. Only 45 of the 635 reports identified met the inclusion criteria. Adherence was consistently associated with patient satisfaction with communication, patient-provider relationship, their treatment, and use of eHealth and mHealth strategies; a patient’s mental and physical health, including depression, cognitive impairment, frailty, and disability, previous hospitalization, occurrence of vital events; drug treatment type and appearance; and unwillingness due to health literacy, self-efficacy, and both implicit and explicit attitudes towards treatment. There were discrepancies regarding the association of other factors to adherence, but these inconsistent factors should also be taken into account. In conclusion, the barriers to adherence are varied and often interconnected between socioeconomic, patient, therapy, condition, and healthcare system levels. Healthcare teams should invest in studying patients’ non-adherence motives and tailoring interventions to individual levels, by using a multifaceted approach to assess adherence. Further research is needed to analyze the impact of implicit attitudes, the use of new technological approaches, and the influence of factors that are inconsistently associated with non-adherence, to understand their potential in implementing adherence strategies.
  • Multimorbidity daily life activities and socio-economic classification in the Central Portugal primary health care setting: an observational study
    Publication . Santiago, Luiz Miguel de Mendonça Soares; Prazeres, José Filipe Chaves Pereira; Boto, Tânia; Mauricio, Katia; Rosendo, Inês; Simões, José Augusto Rodrigues
    Background. Multimorbidity (MM) is associated with decreased quality of life, mainly due to decreased functional capacity and increased use of health care. Objectives. Evaluate the prevalence of MM in older people of Central Portugal and understand the impact of MM on daily life activities (DLA) and how socioeconomic level influenced prevalence of MM. Material and methods. Observational study of data on age, sex, number of ICPC2 codes and Barthel (Bt) and Graffar (Gr) Indexes in clinical records of all aged between 65 to 99 years enrolled in the Health Centers of the Central Region of Portugal. The Bt was used to assess the dependence on DLA and the Gr the socioeconomic level. Results. Population of 190025, mean age of 80.16± 8.03 years. MM prevalence of 80% out of which, 52.9% were female and the majority was aged between 76-85 years (39.1%). Average number of health problems of 8.7 problems for males and 9.5 for females. The Bt and Gr Indexes filling for the studied sample were of, Barthel 7.4% and Graffar 4,9%. Older people without MM have higher dependency rates than those with MM (total dependence 7.4% vs 6.2% and severe dependence 20.1% vs 9.6%). MM in older people are mainly in the middle (55.3% vs 27.5%) and low (31.8% vs 19.6%) Graffar class, while the older people without MM are mainly at middle to upper (35.3%) and upper (17.6%) Graffar classes. Conclusions. Multimorbidity is mainly associated with lower social classes. Dependence for DLA appears unrelated to MM. Multimorbidity persons need special attention, based on socio-economic contexts.
  • Cross-cultural adaptation and validation of the PRISMA-7 scale for European Portuguese
    Publication . Santiago, Luiz Miguel de Mendonça Soares; Silva, Raquel; Velho, Denise Alexandra Cunha; Rosendo, Inês; Simões, José Augusto Rodrigues
    Background. Frailty is an age-associated biological syndrome and a predictor of multimorbidity outcomes, whose early recognition allows for the identification of those older patients at risk. The PRISMA-7 scale allows for the identification of frail older people. Objectives. To make a cross-cultural adaptation and validation of the PRISMA-7 to the European spoken Portuguese language. Material and methods. Cross-cultural adaptation by translation of the PRISMA-7 scale into European Portuguese, debriefing and back-translation to English. Application for intra-observer reliability assessment and validation by simultaneous and concurrent application of the Katz scale. Results. Cronbach’s alpha coefficient was of 0.420 and 0.409 after a re-test. Spearman’s Rank Order Correlation of 0.969 in the re-test operation in a sample of 64 older people (35 female). More than 3 affirmative answers were found for older people (p < 0.001), for a higher number of self-reported drugs taken, (p = 0.001), self-reported years of education (p = 0.001), higher values for those with less years of studies were found in the validation of the translated PRISMA-7 scale, in a purposive sample of 127 older people, 72 (56.7%) female. No differences were found between gender (p = 0.414) and for number of self-reported diseases (p = 0.258). A Spearman correlation of ρ = 0.477 (p < 0.001) between the total of the two scales was found. Discussion. This comprehensive tool enables health care providers to discuss and architect more effective and efficient measures for these patients’ care, regardless of gender, socio-demographic factors, number of self-reported drugs taken and diseases. Conclusions. The PRISMA-7 scale is now recommended to identify frail older people in the Portuguese community.
  • Patients’ and tutors’ evaluations of medicine students’ consultations in general practice/family medicine in Coimbra
    Publication . Santiago, Luiz Miguel de Mendonça Soares; Caetano, Inês; Simões, José Augusto Rodrigues
    Background Undergraduate teaching of General Practice/Family Medicine (GP/FM) must ensure students acquire the necessary competencies and skills to perform an adequate GP/FM consultation with adequate annotations (the SOAP model) and classifications. So aimed to study and to correlate students’ evaluation by tutors and patients in specific consultations in the formal practical evaluation of GP/FM Curricular Unit of the Integrated Masters on Medicine at the Faculty of Medicine of the University of Coimbra (IMM-FMUC) in the academic years of 2017–2018 and 2018–2019. Methods Observational study of the 2017–2018 and 2018–2019 academic years of the assessment grids for tutor’s evaluation of SOAP performance and fluency in consultation and for patient’s evaluation of the student ‘performance, in the convenience sample of those who chose to be so evaluated. Results We studied a population of 435 (67,7%) out of a universe of 646 students, 125 (28,7%) males, ns by sex and academic year who performed this evaluation. In a mark up to 20 from tutors, difference was found for Plan (P) mark, higher in 2018–2019 (18,38 ± 2,18vs18,54 ± 2,11, p = 0,005) of the SOAP methodology evaluation. Patients’ evaluation was not different 19,34 ± 1,70vs19,35 ± 1,40, p = 0,091. A positive significant correlation was found between tutors and patients marks (ρ = 0,278; p < 0,001), as well as between tutor mark and final mark (ρ = 0,958; p < 0,001) and patient and final marks (ρ = 0,465; p < 0,001). Final marks were not different in both years, 18,61 ± 1,38vs18,78 ± 1,15, p = 0,158. Conclusions This innovative model of evaluation of student’s performance in medical appointment, showed a significant positive moderate correlation between patients’ and tutors’ marks in the setting of GP/FM at the IMM-FMUC, and was not different between years. Yearly evaluation must be continued.
  • Carta ao Editor a Propósito da Carta ao Editor “Polifarmácia e Utilização de Medicação Potencialmente Inapropriada no Idoso com Idade Igual ou Superior a 75 Anos: O Caso de uma Unidade de Saúde Familiar”
    Publication . Simões, Pedro Augusto Gomes Rodrigues Marques; Santiago, Luiz Miguel de Mendonça Soares; Simões, José Augusto Rodrigues
    Caro Editor, Lemos com interesse a carta ao editor acerca da polifarmácia e utilização de medicação potencialmente inapropriada (MPI) no idoso com idade igual ou superior a 75 anos.Num estudo similar, desenvolvido no âmbito dos Cuidados de Saúde Primários a nível nacional e com uma amostra representativa de 757 idosos com idade igual ou superior a 65 anos de acordo com a distribuição a nível nacional da população idosa, verificámos uma prevalência de polifarmácia de 77% (sobe para 82,6% quando consideramos a faixa etária ≥ 75 anos) e uma média de 8,2 medicamentos (8,7 medicamentos se ≥ 75 anos). A prevalência de pelo menos uma MPI foi de 68,6% (sobe para 72,1% se considerarmos apenas ≥ 75 anos), e os MPI mais prevalentes foram os inibidores da bomba de protões (presentes em 45,6% da nossa amostra), anti-inflamatórios não esteroides (em 34,5%) e benzodia-zepinas (em 27,3%). As diferenças encontradas dever-se-ão, provavelmente, às caraterísticas específicas da população estudada, bem como aos métodos de recolha de dados, informações que não ficam claras numa exposição tão curta como a feita em formato de carta ao editor. No nosso estudo verificámos que a probabilidade de um idoso estar sujeito a polifarmácia au-menta com a idade, número de doenças crónicas e o número de prescritores; enquanto que a probabilidade de um idoso estar sujeito a medicação potencialmente inapropriada aumenta com o ser mulher, número de doenças crónicas, número de medicamentos e número de prescritores. Concordamos e sublinhamos a importância dada à necessidade de ser revista periodicamente a medicação dos nos-sos utentes, principalmente dos mais idosos que têm maior probabilidade de sofrer eventos adversos aos medicamentos. Salientamos a necessidade de prescrição criteriosa dos medicamentos, com a utilização de ferramentas de apoio, sendo os critérios de Beers um bom exemplo de tal. Mas o uso de critérios implícitos que envolvam o nosso juízo clínico, de que os exemplos mais conhecidos são o Medication Appropriateness Index e o algoritmo de Garfinkel, devem ser referidos para utilização criteriosa. Uma vez que em muitos casos a medicação prescrita é apenas a ponta do iceberg do que os utentes tomam, devendo também considerar-se a toma de medicação de venda livre e de suplementos, cuja prevalência de consumo tem vindo a aumentar, mais importante ainda se torna este tema que deve ser baseado no conhecimento a adquirir ao nível pré--graduado e modelado pelas ferramentas acima referidas como auxiliares da melhor prática.
  • A Escolha da Especialidade Médica: Podem os Professores Universitários Influenciar na Decisão?
    Publication . Prazeres, José Filipe Chaves Pereira; Passos, Lígia; Loureiro, Manuel; Simões, José Augusto Rodrigues
    A carreira profssional médica inicia-se com a importante decisão pela especialidade a ser seguida. Usualmente a escolha dos futuros especialistas é influenciada por factores pessoais (personalidade, estilo de vida, valores e interesses), pelas características da própria especialidade, além de experiências prévias. O contacto com a especialidade durante a formação pré-graduada pode ainda ser considerado um fator influenciador na escolha, visto que a sensibilização para a Medicina Geral e Familiar (MGF) teve alguma relevância para 23,4% dos médicos, num estudo anterior.
  • Prevalence of polypharmacy in the older adult population within primary care in Portugal: a nationwide cross-sectional study
    Publication . Simões, Pedro Augusto Gomes Rodrigues Marques; Santiago, Luiz Miguel de Mendonça Soares; Simões, José Augusto Rodrigues
    Introduction Polypharmacy is commonly defined as the simultaneous use of five or more medications; however, there is a lack of consensus regarding the most appropriate definition. It is a significant predictor of morbidity and mortality. The aim of this study was to determine the prevalence of polypharmacy in the population of older adults attending primary care in Portugal and to identify associated sociodemographic and clinical factors. Material and methods We conducted a cross-sectional, analytical study in primary care centres from the five Portuguese healthcare administrative regions and the two autonomous regions. We used a random sample of 757 older adult patients provided by the information department of the ministry of health (SPMS) and family doctors from the autonomous regions. Data collection occurred in March 2018. The variables utilised were sociodemographic characteristics, clinical profile and medication. For each patient, polypharmacy was measured either by the concurrent use of ≥ 5 drugs or by the median number of drugs at the time of data collection. Logistic regression analyses were performed to determine associations between polypharmacy and other variables. Results Polypharmacy (≥ 5 drugs) was present in 77% of the sample. A cut-off of over the median number of drugs was present in 55%. The likelihood of having polypharmacy increased significantly with age (OR = 1.05 (1.02–1.08)), number of chronic health problems (OR = 1.24 (1.07–1.45)) and number of prescribers (OR = 4.71 (3.42–6.48)). Cardiovascular, metabolic and musculoskeletal medications were the most commonly involved in polypharmacy. Conclusions Polypharmacy was a very common occurrence in Portugal. Future primary healthcare policies should address polypharmacy.